Looking For Eflornithine Manufacturers In China?
Contact Us Now!

Why You Should Buy Eflornithine Hydrochloride From Us

#1. High Purity:

Our purity is 98% as min, actual data always pass 99%.

#2. Quality guarantee:

You can have a full refund in case you have any quality issues.

#3. Sample For Quality Approval Available

Spectrums available: HPLC, 1HNMR

#4. Low MOQ:

Our MOQ starts from 100G

#5. Short Lead time:

Prompt shipment for your order of kilos

What Is Eflornithine Hydrochloride (Vaniqa)?

Eflornithine Hydrochloride Hydrate Chemical Structure

Cas No.: 96020-91-6

Molecular Formula: C6H15ClF2N2O3

Eflornithine HCl a is a white to off-white solid with a purity of 98% or 99%. Different purities mean different prices.

It is one of our main bulk cosmetic ingredients along with cosmetic-grade Minoxidil.

It is mainly used in the treatment of female facial hirsutism.

It can be indicated alone or in combination with spironolactone for different situations.

Eflornithine has been made into topical creams for women suffering from facial hirsutism under the brand name Vaniqa.

Eflornithine is also made into injections used against sleeping sickness under the brand name Ornidyl in the USA.

But the eflornithine injection is now discontinued. 

It is also an inhibitor of ornithine decarboxylase, while it exhibits high activity in tumor cells.

So eflornithine can also be used for cancers, while the anti-cancer formulations for Eflornithine are very rare to find in the market.

Its anti-tumor activities are still under research in many countries, very few FDAs approve any anti-cancer eflornithine dosages till today.

So, Can Eflornithine Be Used For Cancer?

It has been indicated alone or in combination with other ingredients such as procarbazine, lomustine, vincristine to treat gliomas.

Eflornithine has also been under investigation for the treatment of neuroblastoma.

Researches have shown that eflornithine will Increase the Survival rate in High-Risk Neuroblastoma.

It can be used for cancer because it irreversibly inhibits one enzyme: ornithine decarboxylase(ODC).

This enzyme exhibits high activity in tumor cells and will promote cell growth and division.

While the activity of this enzyme is inhibited, it will lead to depletion of putrescine, causing impairment of RNA and DNA synthesis.

therefore eflornithine will eventually inhibit the formation and proliferation of tumor cells and act as an anticancer agent.

What is the HS Code for Eflornithine?

Eflornithine hydrochloride is a derivative of the amino acid ornithine.

It is classified as an organic amino acid derivative compound.

Chemically speaking, Eflornithine Hydrochloride Hydrate is an organic compound, a derivative of amino acids.

In China, it is categorized as one group of compounds called ‘other amino acids’ with HS Code as 2922491990.

How Much Does Eflornithine Cost?

For order quantities about 200G, our price by door-to-door is around 6.5USD/G

For 99% type powder, the price is about 4000usd/kg for commercial order quantity over 10kg in China.

Due to the small market demand for eflornithine hydrochloride, there is no eflornithine hydrochloride GMP available in China. (It used to be 2000usd/kg before Jan 2019)

Technical Documents Download

References

Other Ingredients You May Like