Why You Should Buy Vancomycin Powder From Us?

#1. Docs for registration are ready: our GMP/DMF are available for your MOH registration.

#2. Strict quality control: our pure powder meets the requirements of USP/EP

#3. Sample For Testing Are Available: If you need samples for testing, contact us directly.

#4. Low MOQ: our MOQ is 1kilo. If you have less demand than that, we can also help to do the repacking into 100G.

#5. Short Lead time: Goods will be shipped out within 4 days after order.

Looking For Vancomycin Manufacturers In China? Contact Us Now!

What is Vancomycin?

Vancomycin Hydrochloride Structure

Cas Number: 1404-93-9

Molecular Weight:  1485.71g/mol

Molecular Formula: C66H76Cl3N9O24

HS Code: 2941909000

Vancomycin hydrochloride is a white to off-white crystal commonly used as an actitive ingredient for antibiotic injections.

It was a polypeptide firstly separated and made into injections by Eli Lily in 1958.

Vancomycin HCl is used to treat many life-threatening conditions caused by infections, to which those regular penicillins are not effective or for those people allergic to.

It is one of our China GMP certified antibiotics along with Bacitracin, Spectinomycin HCl, Amphotericin B.

Vancomycin has a similar treatment efficacy of pseudomembranous colitis and Clostridium difficile-associated diarrhoea as Teicoplanin.

What Is Vancomycin Used For?

The original purpose of developing vancomycin was to treat patients with infections caused by penicillin-resistant Staphylococcus aureus and patients who are allergic to penicillins.

For several reasons below: vancomycin has never been a first-line drug for the treatment of Staphylococcus aureus infections:

#1. Vancomycin must be administered intravenously because it will not be absorbed orally.

#2. The rapid development of β-lactamase-resistant semisynthetic penicillins.

Penicillins such as methotrexate penicillin (and its successors such as etanercept (amine) penicillin, o-chloramphenicol, etc.) can effectively inhibit penicillin-resistant bacteria, therefore, it doesn’t leave much room for further development of vancomycin.

#3. If the vancomycin is not very pure, it was highly ototoxic and nephrotoxic.

These three findings above led to the downgrading of vancomycin as a “last line” anti-infective drug.

Vancomycin HCl considered as the Last Resort Remedy means it is only recommended when all other antibiotics are not effective to these infections any more.

You can use vancomycin to treat serious, life-threatening infections by Gram-positive bacteria unresponsive to other antibiotics such as sepsis and lower respiratory tract, skin, and bone infections. It has been used to treat many infections in forms of intravenous injections.

Those life-threatening infections include complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus.

Is Vancomycin A Penicillin?

As we mentioned earlier, vancomycin is a polypetide with a huge molecular weight of 1485.71g/mol.

It was developed to treat patients with infections allergic or non-reactive to penicillins.

Penicillin is an antibiotic extracted from Penicillium and later it refers a class of antibiotics that contains penicillin in its molecule, which can destroy the cell wall of bacteria and play a bactericidal role during the reproduction period of bacterial cells.

Penicillin belongs to β-lactam antibiotics, which include penicillin, cephalosporins, carbapenems, monocyclics, cephalosporins, etc.

Though penicillin is a very commonly used antibacterial drug, an intradermal test must be performed to prevent allergy.

You can find the penicillin category as below:

#1. Penicillin G class:

Such as penicillin G potassium, penicillin G sodium, long-acting cillin, etc.

#2. Semi-synthetic penicillins

2.1 Acid-resistant penicillin Penicillin V

2.2 Enzyme-resistant penicillins:

Such as benzathine penicillin (Neosporin II), chlorazolyl penicillin, etc.

2.3 Broad-spectrum penicillins:

Such as ampicillin, hydroxyampicillin (amoxicillin), etc.

2.4 Broad-spectrum penicillins against Pseudomonas aeruginosa:

Such as carbenzylpenicillin, oxybenzyl penicillin, furobenzylpenicillin, etc.

2.5 Azamethicillin (anti-Gram-negative bacillus penicillin):

Such as methicillin and its ester pimecillin, etc., which is characterized as more enzyme-resistant and effective against certain negative bacilli (e.g., Escherichia coli, Klebsiella and Salmonella), but poor against Pseudomonas aeruginosa.

By comparison we can conclude that vancomycin is not a penicillin but a polypeptide antibiotic to treat infections of some extreme cases.

How Much Does Vancomycin HCl Cost?

If you are looking for pure powder approved with Chinse GMP to make injections or other forms of medicines, our cost for commercial order quantities of 100kg or more is around 850~900USD/KG.

Please note, there are two types available in the market: sterile and non-sterile type.

For sterile type, the unit price is around 900USD per kilo, for non-sterile type, the price is lower, about 800usd each kg.

If you can accept non-GMP source for your research, related price offer should be around 500USD/KG.

Here we only supply pharm-grade powder with GMP.

For more accurate prices with other quantities, please contact us directly.

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References

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