Buy 99% Tacrolimus Powder In Stock
Why Buy Tacrolimus Powder From Us?
#1. FDA/GMP approval are available with whole sets of MOH registration docs ready.
#2. High quality APIs suitable for medicine manufacturing after registration: our apis strictly meet requirements of USP monographs.
#3. Quality guarantee: 100% refund or free exchange of goods if not meeting standards of USP
#4. Fast shipping: Goods can be shipped out within 3~4 days afer your order confirmation.
#5. Samples for quality approval and MOH registration are available.
#6. NDC number available, suitable for compounding pharmacies within USA.
Looking For Tacrolimus Manufacturers In China? Contact Us Now!
We have helped our current clients to gain more market shares through our reliable quality and steady supply. We hope you can work with us to further lower your buying cost.
What Is Tacrolimus Powder?
Cas number: 104987-11-3
Molecular formula: C44H69NO12
Molecular weight: 804 g/mol
Existing as an anhydrous or monohydrate form, pure Tacrolimus is a white crystalline powder soluble in many solvents such as ethanol, methanol, acetone and chloroform, but insoluble in water.
It is used to to reduce the activity of the patient’s immune system and the risk of organ rejection after organ transplant. It is one of the most effective immunosuppressants along with Cyclosporine.
Pharmaceutical manufacturers have made into many dosage forms. You can even get its ointments and creams from a compounding pharmacy.
Its common dosage forms include: capsules, injections, eye oitments, solutions, creams, lotions etc. If you are the dosage manufacturer of those dosages above, contact us now for a free quote.
We have been supplying it to many brand manufacturers over the past 3 years, our quality has been very consistent and appraised by current customers.
Tacrolimus vs Cyclosporine
Though tacrolimus is different from cyclosporine in several aspects, such as potency, safety, dosage forms, acting mechanism and so on, the biggest difference to me, as a chemical importer and exporter, is their prices.
If you are a regular buyer for it, you know it is normally sold by GRAM, as regular orders are in 2~300 grams, unless heavy buyers are buying it by kilos each order.
According to one study, it was able to significantly lower rate of acute rejection compared with cyclosporine-based immunosuppression (30.7% vs 46.4%)
We have compared the differences between tacrolimus and cyclsopine in our cyclosprine page, please click to check.
What is HS Code Of Tacrolimus?
In Chinese Customs, its pure powder is classified as Other heterocyclic compounds with HS Code as 2934999090.
If you are importing its finished formulations from China such as capsules, ointments, the corresponding HS Code is 30049099.
How Much Does Tacrolimus Powder Cost? (Last update 2020.09.23)
If you are looking for GMP-and-FDA-Approved Tacrolimus manufacturers, please check our price ideas below:
For commercial order quantities over 1kg, our price is around 60 usd/g. (used to be 90usd/g)
For trial orders of 10g, our price is around 100usd/g. (used to be 200usd/g)
If you only need several grams for research, we also have samples available for prompt shipping.
Please specify if you need GMP or not before your order. The price without GMP can be lower than our offer above.
For more accurate prices, please contact us directly.
You can also check its prices from reagent companies if you have difficulties in making your decisions.
Price from sigma is 1730usd for 150mg
Price from trc-canada is 275usd for 100mg
There are other suppliers you can contact, but if you need reliable suppliers who can guarantee the quality and fast shipment, look no more.
You give us a chance to co-op, you enjoy our second-to-none service. We also shoot a video on how to lower your buying cost for tacrolimus medication, please check below.
Tacrolimus Price Trend Since 2010
As you can see from the above price trends, its cost has dropped from its highest 100usd per gram since 2010 to less than 80usd per gram in 2020.
The price drop is mainly caused by manufacturing-capacity surplus and more foreign competition. But a 20% drop within 10 years is acceptable for an old API.
You can also check its export price from India below for your ref.
As you can see, its export price from Europe to India is around 73~85usd per gram, it is similar to the cost of the GMP source. With those lower prices of 55usd~61 per gram you can only get materials from non-GMP sources, at least it is the case in China.
What To Ask Your Tacrolimus Suppliers Before You Order?
#1. Whether your supplier has the technical package for your MOH registration.
Ask your supplier if they have documents first, such as Good Manufacturing Practice, Drug Master Files, Drug Manufacturing License, FDA, CEP, etc. Without those docs and proper registration papers, you will have trouble in your customs for your import.
#2. Whether your supplier can arrange safe shipping by air.
To ship chemicals by air, the exporter of chemicals must apply for the certificate of safe air transportation from relevant authorities. It is regarded as a 6.1 type of dangerous goods. You need suppliers who can handle the proper shipping by air for you.
#3. Whether your supplier has a quality guarantee.
Ask your supplier if they can guarantee their quality, whether they have a full refund or goods-exchange policies for any quality issues. You can add those refund or goods-exchange terms into the sales contract before ordering.
#4. Whether your supplier has any reference from their current customers.
A good reference from their current customers will definitely make your supplier more trust-worthy.
If you have positive and satisfactory answers from your chemical suppliers, you can go ahead to order from them.
How Do You Ship And Store Tacrolimus Powder?
#1. How to transport and at what temperature
As it is a very expensive API, even the quantity for a commercial order is in kilos, 10 kilo is a huge order already. So there are not many shipping options left for its transport: we either ship it by air or by courier.
There is one issue for shipping chemicals by air, shipper must apply for one copy of certificate of safe air transportation. Without it, the airlines or shipping companies will not ship it. The trick with tacrolimus powder is that it is tested as a 6.1 type dangerous chemical in some cities, where you can only ship it by air through airlines for hazardous goods. No courier is shipping dangerous chemicals in China mainland.
As for the shipping temperature, it is recommended to be shipped at 2~8 degrees celsius. Though we have shipped samples by normal temperature to some customers and later testing shows quality is not tampered anyway. Still we recommend shipping at low temperature.
#2. How do you store it after you receive it.
For long-term storage, it is recommended to be stored in air-tight container, protected from light and moisture at -20 degrees celsius. The shelf life at this temperate is 2 years as min. Just make sure retest it before you use it.