What Is Tafamidis 594839-88-0?
Tafamidis is a novel active pharmaceutical ingredient used to delay the loss of peripheral nerve function in adults with familial amyloid polyneuropathy (FAP). It works by stabilizing the protein and transthyretin, which is made up of four strands. In people with FAP, these strands would separate and form clumps to harm nerves.
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Basic Information For Bulk Tafamidis Powder
Product name: Tafamidis
Appearance: white to off-white powder
Cas #: 594839-88-0
Chemical name: 2-(3,5-Dichlorophenyl)-6-benzoxazole carboxylic acid
Molecular Weight: 308.11
Molecular Formula: C14H7Cl2NO3
Is tafamidis available in the US?
Yes, tafamidis was approved by the FDA for the treatment of transthyretin-mediated cardiomyopathy in March 2019.
Tafamidis brands include Vyndaqel(Tafamidis meglumine) and Vyndamax(Tafamidis). The FDA approved tafamidis meglumine as an orphan drug, while European Medicines Agency made tafamidis an orphan drug rather than Tafamidis meglumine in Europe.
What is the difference between tafamidis and tafamidis meglumine?
Tafamidis Meglumine Structure
There are two tafamidis forms in the USA: Tafamidis meglumine and tafamidis. Despite their differences in chemical physical and chemical properties, those two have the same active moiety and the effect in the body is almost the same.
What are tafamidis side effects?
Before you take the medicine, you need to ask the doctor or pharmacist of the tafamidis side effects. The most common tafamidis side effects include urinary tract infection, vaginal infection, diarrhea, and upper abdominal pain. So please take extra care before you take it.
What is Tafamidis synthesis route?
2-step reactions to get tafamidis powder
As you can see from above, tafamidis is synthesized in 2 steps: first through addition reaction of 3,5-Dichlorobenzoyl chloride and 4-Amino-3-hydroxybenzoic acid. Second step is dehydration reaction to get pure tafamidis crystals.
What is tafamidis meglumine cost?
For 100G Tafamidis or meglumine salt, our Fob Shanghai Price is around 120USD/G.
For 1kg Tafamidis or meglumine salt, our price is around 100USD/G
For more accurate tafamidis prices, please contact us directly.
Where to buy tafamidis pure powder?
If you are a patient, you can get this drug from the USA, Europe, Japan now.
But if you are a scientist needing tafamidis for research, email us or call us now! We have pure tafamidis in stock with the HPLC purity > 99%.
We will provide Tafamidis NMR and HPLC spectrums for your confirmation before your order.
Many reagent companies are buying from us. You can check tafamidis prices from reagent companies below for your ref:
Tafamidis price from selleck chem is around 800usd/100mg
Tafamidis price from chem scene is 450usd/100mg
Tafamidis price from adooq is 90usd/10mg
Tafamidis price from MCE is around 1000usd/100mg
From the prices above you can see the best tafamidis price is from chem scene. Their price is 450usd/100mg without shipping cost.
Tafamidis cost of commercial order quantities from octagonchem is 120usd/g. If you are looking for tafamidis for research, look no more! Octagonchem will be your first choice for tafamidis powder.