98% Vitamin K2 (MK-7) Powder Supplier In China
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Why Choose Us As Your Vitamin K2 Supplier In China?
#1. High purity with our consistent manufacturing process:
Our MK-7 powder is 98% as min and the testing results are often 99% or more.
#2. Low heavy-metal content and strict microbial CFUs:
We keep our standards of mercy content below 0.03 ppm and arsenic less than 1 ppm.
We make sure the VK2 powder is as safe as possible. Our MK7 has been used by many Nutrition Brand Manufacturers in China. The safety and efficacy are rock-solid.
#3. Steady stock with fast shipment:
Though the bulk menaquinone-7 powder is super expensive and sold by grams, we keep kilos in stock so we can make sure our customers get supplied in time.
What is Vitmain K2 (MK-7)?
Cas Number: 2124-57-4
Molecular Weight: 649 g/mol
Molecular Formula: C46H64O2
Chemical Name: 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaenyl]-3-methylnaphthalene-1,4-dione
HS Code: 2936290090 (其他未混合的维生素及其衍生物-Other unmixed vitamins and their derivatives)
VK2(Menaquinone-7), also called Trans-MK7 or Vitamin K2(35), or methylnaphthoquinone-7, is a yellow crystalline powder, mainly extracted from natural foods, especially natto.
MK7 is insoluble in water but soluble in lipids.
VK2 is one of the two most commonly seen Vitamin K along with Vitamin K1. (Vitamin K has VK1, VK2, VK3, VK4, while MK starts from MK2 and goes all the way to MK14)
Vitamin K1 is from green leaves, while Vitamin K2(MK7) is from fermented foods.
It is also the most expensive version of the Vitamin K series. (One kilo of Vitamin K1 oil 98% type in 2021 costs 2000USD, while 1 gram of 98% MK7 costs 450USD or more)
The cheaper version is VK2 is menaquinone-4 or MK4 or Vitamin K2(20).
How is Vitmain K2 (MK7) Manufactured?
Speaking of the production of MK7, we must say something upfront: there is no such thing as natural vitamin k2 (MK7), ok?
Even if there is, it can’t be extracted from plants, then it must be fermented and extracted from certain germs.
Almost all the MK7s you can find in the market are chemically synthesized, not naturally extracted from plants or mushrooms, etc, just like almost all conventional vitamin d3s are of animal origins.
If some supplier is claiming that their vitamin d3 powder is vegan or extracted from plants, you need to watch out, you are to be misled.
Ok, back to our topic: how is MK7 produced?
Here we just give you guys one general way of synthesis for all MK series.
Check this synthesis route below:
From the synthesis method above, you can synthesize any MK you like, just choose the right reaction conditions.
If you need more details on its synthesis, welcome to contact us directly.
What is Vitmain K2 Used For?
VK2(MK-7) is formed during the fermentation process, and it has two main advantages.
It stays in your body longer and has a long half-life, which means that you only need to take it once daily.
Research has found that MK-7 can help prevent inflammation by inhibiting pro-inflammatory markers that may contribute to autoimmune diseases such as rheumatoid arthritis.
While studies have found that vitamin K1 can modestly reduce the risk of fractures, MK-7 is more effective at reaching the bones than vitamin K1.
In your bones, vitamin K2 is used to produce osteocalcin, which improves metabolism, hormone health, and athletic performance.
We have compiled the benefits of VK2 below:
#1. Cardiovascular protection and cofactor for vitamin D and calcium absorption.
Calcium deposits in the arteries can lead to atherosclerosis, hardening, and narrowing of the arteries, which gradually impede blood flow.
This is a common cause of heart attacks, strokes, and peripheral vascular disease.
Vitamin K2 is essential for activating important proteins, such as matrix GLA protein (MGP), found in your vascular system, and studies have demonstrated that K2 inhibits arterial calcification and improves arterial flexibility, thereby reducing the risk of atherosclerosis.
A recent study suggested that therapeutic supplementation with vitamin K2 may prevent or stop possible vascular calcification, and other studies have demonstrated that people who consume the most vitamin K2 also have the lowest risk of cardiovascular disease.
Vitamin K2 is also an important cofactor for calcium and vitamin D.
While calcium is important for strengthening bones and enhancing overall bone health, it can only work if it is delivered to the right place in your body.
Vitamin K2 prevents calcium from being deposited along the walls of blood vessels and directs it to the bones.
Therefore, it is important to remember that vitamin K2 and vitamin D (along with calcium and magnesium) work synergistically for your bone and heart health.
To get as much benefit as possible from oral vitamin D supplements, it is important to maintain optimal levels of vitamin K2.
Studies have shown that supplementing with both vitamin D3 and vitamin K2 is more beneficial to cardiovascular health than vitamin alone.
#2. Vitamin K2 helps prevent osteoporosis and protects teeth
As mentioned before, the action and function of vitamin K2 activate osteocalcin, a protein hormone produced by bones, which requires vitamin K2 to be activated by carboxylation.
One of the main roles of osteocalcin is to bind to calcium and transport it to the bone.
Osteocalcin is a tiny non-collagenous protein that can be detected in serum and synovial fluid samples from patients with osteoarthritis, and researchers believe that serum osteocalcin levels may be a practical screening tool for assessing osteoporosis risk.
The role and function of vitamin k2 are also critical to oral health.
It preserves tooth enamel and prevents tooth decay formation.
Tooth enamel consists of hollow tubes that extend into the dentin.
While enamel is composed of inactive cells, dentin contains active cells called “dentinogenic cells”.
These cells use vitamin K2 to release proteins that prevent tooth decay through an immune response.
Studies have shown that osteocalcin may be present in inflamed tissues, and researchers believe that this protein can play a restorative role in the dental pulp.
#3. Vitamin K2 plays a role in reducing inflammation and promoting kidney health
The inflammatory response is a key component of many chronic and age-related diseases. Scientific evidence suggests that both vitamin K1 and vitamin K2 have anti-inflammatory activity, partly due to their ability to inhibit nuclear factor κB.
For example, researchers found that vitamin K protected chronic aging, inflammation, and cardiovascular disease.
Another study confirmed the specific role of the MK-7 form of vitamin K2 in regulating biomarkers of inflammation.
Researchers evaluated the potential of natural vitamin K2 to inhibit gene expression and the production of pro-inflammatory markers in an in vitro assay and found that the MK-7 inhibited gene expression in a dose-related manner.
Another study found a reduction in C-reactive protein, a common biomarker used to measure levels of inflammation in patients with rheumatoid arthritis.
C-reactive protein is a risk marker for a variety of diseases, from which researchers concluded that a higher intake of vitamin K2 may reduce overall disease risk.
There is growing evidence that the role and function of vitamin k2 may have implications for chronic kidney disease.
A pre-and post-intervention clinical trial recruited participants diagnosed with chronic kidney disease and asked them to take vitamin K2 MK-7 for four consecutive weeks, and found a significant reduction in vascular calcification in these patients.
Patients with chronic kidney disease who have subclinical vitamin K deficiency may also benefit by increasing their intake of MK7.
Don’t forget that vitamin K2 is a fat-soluble vitamin, so it is best to take a small amount of fat along with it to promote absorption.
Eating foods rich in vitamin K2 is your best bet.
MK-4 is found in many animal foods such as eggs (especially egg yolks), dark chicken, and goose liver.
MK-7 is usually found in fermented foods such as natto (a fermented soybean) and cheeses.
Why Should Vitamin D3 And Vitamin K2 Be Used Together?
From 1st point of the benefits of Vitamin K2 is to protect your heart and promote calcium absorption.
How does it work anyway? Why it is called the cofactor of vitamin d?
This is how!
Once you have taken vitamin d3 to strengthen your bones, it may not work as well as you planned.
Vitamin d3 surely can increase the calcium levels in your blood, the key is calcium absorption.
How can you make sure those increased calciums are absorbed properly by your bones, rather than placed where else?
This is where Vitamin K2 comes in.
As the high levels of blood calcium will deposit in arteries without the help of vitamin k2, it will cause heart diseases gradually.
While Vitamin K2 will promote blood calcium absorption by the bones by activating certain proteins.
Jim Beakey used to describe the relation between Vitamin K2 and D3 like this: 1+1=3.
We quoted his words: Vitamin K2 promotes bone and heart health by activating two proteins that balance calcium in the body.
K2 MK-7, the superior form of K2, activates the osteocalcin proteins that incorporate calcium into bones.
Meanwhile, vitamin D3 aids calcium absorption into the blood and has been linked to a reduced risk of breast cancer.
How Much Does Bulk Vitamin K2 Powder Cost?
There are 2 common types of VK2 in the market, 98% pure powder and other low-percentage powders mixed with excipients, such as 1%, 5%, 10%, 20%, etc.
As we compared the prices for pure Vk1 oil and VK2(MK-7) powder from the section above, the price of menaquinone-7 powder is super high.
If you only buy several grams, it costs about 350usd per gram.
If you can raise your order quantity to 50 grams or 100 grams, the unit price will be brought down to 300 USD per gram.
If you are a heavy buyer and you order it in kilos, we can discuss strategic partnerships, and then you can get special offers.
Anyway, the prices of MK-7 are not fixed and will fluctuate with the raw material cost.
With the increasing costs of labor, utility, water, rent, management, etc, the price of Vitamin k2 is on the rise on yearly basis.
The price for Vk2 has doubled in 10 years, increasing the rate by 10% each year.