99% Bulk Calcium 2-Oxoglutarate Of ISO Factory
Calcium 2-oxoglutarate—also known as Calcium Alpha-Ketoglutarate, Ca-AKG, or Calcium Ketoglutarate Monohydrate—is the calcium salt form of alpha-ketoglutaric acid, a critical intermediate in the Krebs cycle (citric acid cycle).
Our Bulk Calcium 2-oxoglutarate powder is manufactured under strict quality controls, with full traceability from raw material sourcing to finished powder.
Whether you’re formulating longevity therapeutics, metabolic health compounds, or specialized nutritional interventions, we provide the pharma-grade foundation your formulations deserve—at scale, on time, and within spec.
Why You Should Buy Calcium 2-oxoglutarate From Us?
#1. High quality:
Our assay is 99% as min, and our manufacturing process has been consistent for the past 4 years.
#2. Quality guarantee:
100% refund for any quality issues
#3. Samples for quality approval available:
You can ask us for a sample to test the quality
#4. Short Lead time:
We have a steady supply of it, over 300 kg, and we can ship it within 3 to 5 days after your order confirmation.
Calcium 2-Oxoglutarate Raw Material Applications
For Pharmaceutical Manufacturers
Longevity & Metabolic Health Therapeutics
Research has demonstrated that alpha-ketoglutarate levels decline with age. Calcium 2-oxoglutarate supplementation has been studied for its potential to extend healthy lifespan, support mitochondrial function, and reduce the incidence of age-related conditions, including osteoporosis, chronic kidney disease, and gastrointestinal disorders. Studies at the Buck Institute for Research on Aging have shown that Ca-AKG may slow aspects of the aging process.
Bone Health Formulations
By delivering calcium in a metabolically active form, Ca-AKG supports bone density while simultaneously participating in energy metabolism. This dual action makes it particularly valuable for the prevention and management of osteoporosis, especially in elderly or postmenopausal populations.
Kidney & Phosphate Management
Calcium 2-oxoglutarate binds excess phosphate in the body, helping re-establish normal calcium-phosphate balance. This mechanism has therapeutic implications for patients with hyperparathyroidism and chronic kidney disease.
Sports Medicine & Recovery
The compound supports muscle protein synthesis, lean mass preservation, and post-exercise recovery by optimizing the energy metabolism required for muscle growth and repair.
For Compounding Pharmacies
Custom Formulations
The moderate solubility and stability of Calcium 2-oxoglutarate make it an excellent candidate for custom-compounded preparations. Its compatibility with various excipients allows for flexible formulation design.
Combination Therapies
Ca-AKG pairs well with other metabolic intermediates, amino acids, and mineral supplements, enabling compounding pharmacists to create targeted combination therapies for:
Metabolic support protocols
Anti-aging and longevity regimens
Post-surgical recovery formulations
Nutritional support for chronic disease management
Research & Development
For pharmacies engaged in clinical research or personalized medicine, our pharmaceutical-grade Ca-AKG provides the consistency and purity required for reproducible results.
Why Pharmaceutical & Compounding Professionals Choose Us
1. Pharmaceutical-Grade Quality Assurance
Every batch is tested using HPLC methodology with full COA documentation. Our quality system meets the expectations of pharmaceutical manufacturers who demand:
Heavy metal testing within pharmacopeia limits
Microbial contaminant screening
Residual solvent analysis
Batch-to-batch consistency verified by third-party labs upon request
2. Manufacturing Transparency
Unlike suppliers who obscure their production methods, we’re proud of our process. Our Calcium 2-oxoglutarate is produced via enzymatic conversion from L-glutamic acid—a cleaner, safer alternative to chemical synthesis routes that involve potentially genotoxic substances such as methyl acrylate. This enzymatic approach:
Eliminates genotoxic impurities at the ppm level
Produces food-grade and pharmaceutical-grade material suitable for human consumption
Ensures smoother processing with fewer post-treatment steps
3. Flexible Supply Chain
Bulk quantities from kilograms to metric tons
Custom packaging to match your production line requirements
OEM services available for private labeling
Global logistics with reliable shipping timelines
4. Technical Support You Can Rely On
Our team includes chemists and formulation specialists who understand the nuances of integrating Ca-AKG into:
Tablet and capsule formulations
Powder blends and sachets
Liquid and suspension systems
Research-grade cell culture media
FAQs About Our Calcium 2-oxoglutarate in bulk?
What is the CAS number for Calcium 2-oxoglutarate?
The CAS number is 71686-01-6. Some suppliers may also reference 402726-78-7 for specific hydrate forms.
What purity levels do you offer?
We supply Calcium 2-oxoglutarate at ≥98% purity as measured by HPLC, with 99% available upon request.
What packaging options are available?
Standard packaging includes 1kg bags and 25kg drums, with custom packaging available for larger orders. We can accommodate specific requirements for your production line.
Is this product suitable for pharmaceutical use?
Yes. Our Calcium 2-oxoglutarate is manufactured to pharmaceutical-grade standards with full documentation, including COA, MSDS, and TDS. We maintain rigorous quality control for heavy metals, microbial contaminants, and residual solvents.
What is the shelf life?
24 months when stored in a cool, dry place in the original packaging.
How is Calcium 2-oxoglutarate produced?
We use an enzymatic conversion process starting from L-glutamic acid—a method that avoids potentially genotoxic substances and ensures food-grade quality. This approach eliminates the need for harsh chemical reagents and produces a cleaner final product.
What applications is this ingredient used for?
Ca-AKG is used in pharmaceutical formulations to support longevity, metabolic health, bone health, kidney function, and sports nutrition. It also serves as a key intermediate in cell culture media and research applications.
What is the difference between Calcium 2-oxoglutarate and Alpha-Ketoglutarate (AKG)?
Calcium 2-oxoglutarate is the calcium salt form of AKG. It offers slower absorption and a more prolonged release profile compared to free AKG, making it suitable for sustained metabolic support. It also provides the added benefit of bioavailable calcium.
Can you provide samples for testing?
Yes, we offer samples for quality verification and formulation development.
Do you provide OEM services?
Yes, we offer comprehensive OEM services, including custom formulations, private labeling, and packaging to your specifications.
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