Source 98% Astragaloside IV Bulk Powder From ISO Factory
Astragaloside IV Bulk Powder is the active pharmaceutical ingredient behind a new generation of cardiovascular, anti-aging, and immune-support formulations worldwide.
As the primary bioactive triterpenoid saponin isolated from the roots of Astragalus membranaceus—one of the most widely used herbs in traditional Chinese medicine for over 2,000 years—Astragaloside IV has emerged as one of the most scientifically validated and commercially significant natural compounds in the global nutraceutical, pharmaceutical, and cosmetic industries.
Pharmaceutical and nutraceutical manufacturers are increasingly investing in research to unlock new therapeutic uses for Astragaloside IV, particularly in cardiovascular health, immune modulation, and anti-aging.
The cosmetics industry is also capitalizing on the ingredient’s reputed anti-aging and skin-rejuvenating benefits by integrating Astragaloside IV into serums, creams, and other topical formulations.
Why Import Astragaloside IV Powder In Bulk Here?
Fast shipment after your order with superior quality
We can ship the goods within 4~5 days for orders under 10 kg.
If you have orders for 100 Grams, 200 Grams, etc., we can also quickly repack and have goods ready in 1~2 days.
For 98% Astragaloside IV, the DMSO solution at 100mg/1ml will be clear. When it is not clear, it is not pure enough.
Quality Guarantee
We have a full refund policy for any quality issues, whether purity or microbial limits.
We can exchange another batch for you at no extra cost, and we will cover your import duties for the second shipment. We will also offer a specific discount for the inconvenience.
Astragaloside IV Bulk Powder Applications and Specifications
Pharmaceutical & Drug Development (Fastest-Growing Segment)
Astragaloside IV is being explored for its potential to support therapies in oncology, diabetes management, and neuroprotection. Key applications include:
Cardiovascular disease therapeutics — myocardial protection, ischemia/reperfusion injury prevention, hypertension management
Oncology support — apoptosis induction, cell cycle regulation, chemosensitivity enhancement
Diabetes management — glucose metabolism improvement, insulin sensitivity enhancement
Neuroprotection — Parkinson’s disease, cognitive deficits, neuroinflammation inhibition
Anti-fibrotic therapies — systemic sclerosis, renal fibrosis, cardiovascular fibrosis
Antiviral applications — inhibition of adenovirus replication
Dietary Supplements & Nutraceuticals (Largest Volume Segment)
Astragaloside IV is widely used as a dietary supplement to enhance immune function. Key applications include:
Immune support formulations — enhancing natural immunity and resilience
Cardiovascular health supplements — supporting heart function and healthy blood pressure
Anti-aging supplements — protecting against oxidative stress and cellular aging
Sports nutrition — reducing exercise-induced oxidative stress
Adaptogenic formulations — supporting stress resilience and overall wellness
Metabolic health — supporting glucose and lipid metabolism
Cosmetics & Personal Care (Rapidly Growing Segment)
Astragaloside IV is increasingly incorporated into premium skincare formulations for its anti-aging, antioxidant, and skin-protective properties:
Anti-aging serums and creams — reducing fine lines and wrinkles
Skin-brightening formulations — improving skin tone and hydration
Protective skincare — defending against UV-induced oxidative stress
Barrier repair creams — supporting skin structural integrity and resilience
Telomere-protective skincare — addressing cellular aging at the molecular level
Key Clinical Finding: Clinical trials showed improvements in skin hydration, tone, and wrinkle reduction. Astragaloside IV provides telomere protection in both in vitro and in vivo settings.
Functional Foods & Beverages
Astragaloside IV is increasingly incorporated into functional foods and beverages as consumer demand for plant-based health solutions grows:
Functional beverages — health-promoting drinks
Nutritional bars — convenient wellness formats
Fortified foods — everyday nutrition enhancement
Product Name: Astragaloside IV Raw Material (Astragalósido IV, 黄芪甲苷)
Appearance: A white crystalline powder
Solubility: Soluble in DMSO and DMF [DMSO (30 mg/ml), DMF (20 mg/ml)]
Cas Number: 84687-43-4
Molecular Formula: C41H68O14
Molecular Weight: 784.97 g/mol
Chemical Name: (2R,3R,4S,5S,6R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
HS Code: 2938909090 (Other natural or synthetic reconstituted glycosides and their salts, etc.-其他天然或合成再制的苷及其盐等)
Suitability for shipment by air/sea/rail as common goods: suitable. It is safe to be shipped by air as common goods.
Grade: Nutritional Supplement Grade
Purity or Assay: 98% (By HPLC)
Standards: Current Enterprise Standards
Manufacturer Certificates available: ISO
Manufacturer Documents Available: COA/MSDS
Supply Capability: 50 KG per month
MOQ: 0.1 KG
Updated Astragaloside IV Bulk Powder Price Ideas: 6000 USD/KG for 1 KG, including shipping. (Contact us by WhatsApp for more up-to-date prices)
Lead Time: 3~4 days for quantities less than 1 KG, 4~5 days for orders Not More than 10 KG.
Stock Status: Over 20 KG
Shipping Temperature: Room temperature
Storage: -20 °C (Long-Term)
Why Choose Us as Your Astragaloside IV Bulk Powder Supplier?
1. Pharmaceutical-Grade Purity
We deliver Astragaloside IV Bulk Powder with ≥98.0% purity (HPLC-verified), and≥99.0% pharmaceutical-grade purity is available for premium formulations. Every batch undergoes rigorous quality control testing using MS, NMR, and HPLC to ensure identity, purity, and batch-to-batch consistency.
2. GMP-Certified Manufacturing with Full Regulatory Support
Our manufacturing facilities operate under strict GMP conditions with ISO certification. We provide comprehensive documentation for regulatory submissions:
Certificate of Analysis (CoA) per ICH guidelines
Method of Analysis (MOA) documentation
Material Safety Data Sheet (MSDS) in GHS format
Stability data — accelerated and long-term
Complete impurity profile documentation
GMP certification from recognized regulatory authorities
HPLC, NMR, and MS testing reports
3. Advanced Extraction and Purification Technology
Our Astragaloside IV is produced using advanced phytochemical extraction technologies, ensuring:
Exceptional purity and potency — up to 99%+
Superior batch-to-batch consistency
Full traceability — from raw herb cultivation to finished API
Elimination of unwanted impurities
Standardized extraction processes for reliable quality
4. Supply Chain Reliability at Scale
Scalable capacity — From gram-level samples to multi-ton commercial orders
Global logistics — Seamless shipping to the US, EU, Asia-Pacific, and beyond
Flexible packaging — 1 kg/aluminum foil bag, 5 kg/carton, 25 kg/drum (customizable)
Cold chain capability — -20°C storage maintained; hygroscopic and light-sensitive handling
Large inventory — Maintained year-round to ensure rapid fulfillment
Rapid delivery — Samples shipped within 24 hours; bulk orders arranged within 72 hours
Competitive pricing — Cost advantages without compromising quality
5. Technical Partnership for Formulation Success
The Astragaloside IV market is expanding at a remarkable 7.76% CAGR toward USD 3.74 billion by 2034. Success requires a partner who delivers more than just raw material. We help you win by providing:
Formulation optimization support for pharmaceuticals, supplements, and cosmetics
Regulatory guidance for global submissions
Analytical method development support
Custom particle size specifications to meet your formulation needs
Expert technical support from formulation scientists
Dedicated account management with rapid response
6. Compounding Pharmacy and Research Solutions
Small-order flexibility — Custom quantities for compounding and R&D applications
Purity you can trust — High-grade ingredients minimize cross-contamination risks
Technical guidance — Expert advice on storage, processing, and formulation
Reference standard availability — For analytical method development and quality control
FAQs About Our Astragaloside IV In Bulk
What is Astragaloside IV Bulk Powder used for?
Astragaloside IV Bulk Powder is the primary bioactive triterpenoid saponin isolated from Astragalus membranaceus root, used as the active ingredient in pharmaceutical formulations (cardiovascular protection, oncology support, diabetes management, neuroprotection), dietary supplements (immune support, anti-aging, cardiovascular health), cosmetics (anti-aging, skin-brightening, barrier repair), and functional foods. It is the key active component in numerous branded and generic formulations worldwide.
What are the brand names for Astragaloside IV?
Astragaloside IV is the generic name for the active ingredient. It is also known by synonyms including AS-IV, Astragaloside A, Astragalin IV, and Cycloastragenol glucoside.
What purity level do you guarantee for Astragaloside IV Bulk Powder?
We guarantee ≥98.0% purity (HPLC-verified), with ≥99.0% pharmaceutical-grade purity available for premium formulations. Every batch is tested for identity, purity, and quality parameters in accordance with pharmaceutical industry standards.
What documentation do you provide with each order?
Every shipment includes a Certificate of Analysis (CoA), Method of Analysis (MOA), Material Safety Data Sheet (MSDS), and stability data. For regulatory submissions, we provide complete manufacturing process documentation, quality certificates, and HPLC/NMR/MS testing reports.
What are the solubility and storage profiles of Astragaloside IV Bulk Powder?
Astragaloside IV is a white to almost white powder that is soluble in DMSO (100 mg/mL), slightly soluble in methanol, and slightly soluble in pyridine. It is hygroscopic and heat- and light-sensitive. For long-term storage: -20°C (3 years) or 4°C (2 years); shelf life of 24 months at 2–8°C when properly stored.
What are the key market drivers for Astragaloside IV?
Key drivers include: increasing global demand for natural and preventive healthcare solutions; rising prevalence of chronic diseases — cardiovascular diseases alone account for nearly 18 million deaths annually; government-backed initiatives — China allocating billions toward TCM modernization; expanding nutraceutical sector; and growing pharmaceutical integration.
What are the key health benefits of Astragaloside IV?
Astragaloside IV offers multiple scientifically validated health benefits: cardioprotective — protecting the myocardium against ischemia/reperfusion injury; anti-inflammatory — inhibiting TLR4/NF-κB signaling pathway; antioxidant — scavenging free radicals and reducing oxidative stress; anti-aging — elongating telomeres and improving skin hydration, tone, and wrinkle reduction; immunomodulatory — enhancing immune function; neuroprotective — inhibiting TLR4/NF-κB-dependent neuroinflammation; antitumor — inducing apoptosis and regulating cell cycle; and antidiabetic — improving glucose metabolism.
What is the safety profile of Astragaloside IV?
Astragaloside IV has demonstrated a high level of safety in toxicity studies. It has shown no significant toxicity or adverse reactions, with oral administration at therapeutic doses showing no detrimental effects on liver and renal function. Caution is advised during pregnancy due to observed maternal toxicity at high doses in animal studies.
Can you supply Astragaloside IV Bulk Powder for compounding pharmacy applications?
Yes. We supply Astragaloside IV Bulk Powder in quantities suitable for compounding pharmacies. Our powder can be used to formulate patient-specific preparations.
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