Buy 99% Bulk Minoxidil Powder
Why You Should Buy Minoxidil Powder From Us?
#1. GMP & DMF Available: It will be much easier for you to register our raw materials before your production as we have all the docs ready.
#2. Quality Guarantee: We have standards of USP/EP/CP and you can test the goods by corresponding MOA. We will give you full refund or change goods for any quality issues.
#3. Reasonable prices: you will find our price reasonable for the similar quality compared with other Chinese suppliers.
#4. Samples For Testing Available: you can get our sample for testing before order.
#5. Low MOQ: You can get low moq starting from 100G.
#6. Short Lead time: Prompt shimpent after PO: tracking will be provided within 3 working days.
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What Is Minoxidil?
Cas Number: 38304-91-5
Molecular Formula: C9H15N5O
Molecular Weight: 209.253 g/mol
HS Code: 2938909090 (2020.09.11 updated, used to be 2933599090)
Chemical name: 2,4-Diamino-6-piperidinopyrimidine 3-oxide or 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide.
Minoxidil is a white to off-white crystalline powder.
It is barely soluble in water but soluble in propylene glycol, methanol, and ethanol.
Its solubility in water is 2.2mg/ml, while in propylene glycol is 75mg/ml.
What Is Minoxidil Used For?
Minoxidil was first used as a potent direct-acting peripheral vasodilator to lower blood pressure, but it showed a side effect of increased body hair.
Later minoxidil is widely studied and used for male baldness.
Studies had shown that about 40% of men experience hair regrowth after 3–6 months.
It must be applied indefinitely for the continued support of existing hair follicles and the maintenance of any experienced hair regrowth.
It is also used with many other ingredients to achieve better hair-growing effects.
We see many of its topical formulations fortified with finasteride, dutasteride, azelaic acid, tretinin in many hair-growing products.
Studies show that 0.01% Tretinin is able to double its efficacy on growing hair back.
The most well-known brands in the market for hair loss are Kirkland and Rogaine. North America is the leading global market owing to the high adoption of hair-loss treatment products.
According to the American Hair Loss Association, over 80% of men experience hair loss by the age of 50.
Even further, over 21 million women suffer from hair loss problems and about 40% of them opt for active treatments.
The demand for minoxidil is expected to surge due to the aging global population.
According to the United Nations Economic & Social Commission for Asia and the Pacific (ESCAP) in North & Central Asia, the population ratio aged 60 and above will increase to over 24% by 2050.
The video below explain how minoxidil works against hair loss.
The more exiting news is: with the help of other ingredients, the efficacy of minoxidil can be greatly enhanced.
There was a test conducted by scientists for the treatment of hair loss combining tretinoin.
The reason is pretty simple: the scalp of some people who are not responding to minoxidil, will respond after applying tretinoin topically for 4 days.
The video below shows how:
Minoxidil 2% vs 5% vs 10%
There are two common specifications of its topical formulations in the market: 2% type and 5% type, either as topical solutions or aerosol foams or the topical liquids.
You may wonder to youself: which brand is the best for receding hairline and which specification and form should you choose for better hair regrowth.
According to one study conducted by Duke Dermatopharmacology Study Center in 2002, it showed that In men with AGA (Androgenetic Alopecia), Its 5% topical was superior to 2% and placebo in increasing hair regrowth, and the magnitude of its effect was marked (45% more hair regrowth than 2% topical at week 48). Men who used its 5% topical also had an earlier response to treatment than those who used 2% topical. Psychosocial perceptions of hair loss in men with AGA were also improved. Its topical form (5% and 2%) was well tolerated by the men in this trial without evidence of systemic effects.
Its 2% topical solution was approved for the first time in 1991 to treat female hair loss by Upjohn, applied twice daily. In more recent years, its first 5% foam for women was approved in 2014, applied once daily. 5% foam no doubt costs less time and is more convenient to apply. There was a study showing that patients using 5% foam had a mean 32-hair/cm2 or 16% increase, not significantly different from the 14% increase documented in women on the 2% topical solution, but 2% is better than nothing right? Polls are showing that women prefer 5% foam to 2% topical solution.
By comparison, we conclude that topical 5% works better than 2% for hair growth and 5% solution was found to be more effective than 2% in maintaining existing hair and regrowing lost hair.
In general, it has been found that the higher the concentration, the better the effect in terms of treating androgenetic alopecia.
And now you have your answer, choose the brands with higher concentrations.
However, the higher concentration, the more increased risk of adverse side-effects. We can already see 10% even 15% formulations in the market. Please be cautious and consult your doctor before you make any decisions.
Is There Minoxidil For Beard Growth?
Partially influenced beard-star James Harden from Houston Rockets of NBA, to grow a thick beard is getting more and more popular.
Are there any finished topical formulations in the market for growing a thick beard? The ‘official’ answer is NO, as there is no approved formulation in any FDA for beard growth.
But there are many successful cases of men applying it to their faces to get their thick beards.
Actually, you can grow your beard by using any of its topical formulations in the market such as Rogaine, Kirkland, Equate, Tugain, and Lipogaine, etc
What Is The HS Code For Minxodil Powder?
Pure minoxidil powder is an organic compound with a pyrimidine ring.
It used to belong to one group categorized as: other compounds containing pyrimidine rings in the structure (including other compounds containing piperazine rings in the structure), with HS Code as 2933599090.
In 2020 it is categorized in China Customs into 2938909090, compounds of other natural or synthetic reconstituted glycosides and their salts, etc.
If you are buying its medical or cosmetic formulations, the HS code is different. In case you are not about its hs code, feel free to contact us anytime.
How To Dissolve Minxodil Powder For 1HNMR and HPLC?
When we do the testing of 1nmr spectra for any unverified molecules, we often use DMSO(dimethylsulfoxide) as solvent. But it is difficult for us to dissolve it in DMSO.
Our Testing Technican has come up with the idea that a little amount of hydrochloride will greatly increase its solubility in DMSO, and voila, we get the concentration we need to do our 1hnmr. You can find our 1hnmr spectrum with hydrochloride for your ref.
For the method of analysis by HPLC, you can just follow the testing procedure in USP monograph. Of course you can always improvise according to different testing conditions you have.
Anything unclear about the testing methods, welcome to contact us anytime. We also shoot video for it, please check the video as below.
How Much Does Minoxidil Powder Cost?
Before you ask for its prices, please note that there are two grades available:
1. Pharmaceutical grade with GMP&DMF for drug manufacturing.
2. Cosmetic Grade for topical formulations.
The price for commercial order quantity (over 100kg) of pharmaceutical grade in China is around 350usd/kg.
Price for commercial order quantities (over 100kg) of cosmetic-grade is around 300usd/kg.
How To Ship and Store Minoxidil Powder?
#1. Shipping methods:
First thing first, minoxidil powder is tested to be very safe to be shipped by air. It is not flammable, explosive, oxidizing, toxic, etc. It is not a dangerous chemical in any way. So we are free to ship it by courier or air for small quantities. For commercial quantities, it is also ok to be shipped by sea or inland methods.
As it is a safe chemical, no special packing required for its shipping either unlike goods of dangerous type 6.1 or other types.
#2. Shipping and storage conditions:
Stability testing has proved that minoxidil powder is stable for 2 years under room temperature when it is properly stored and protected from direct sunlight and moisture. Therefore, we can ship and store it by normal temperature without any cold-chain requirements.