99% Trilostane Powder For Dogs

Looking For The Largest Trilostane Manufacturers In China?
Contact Us Now!

Why You Should Buy Trilostane Powder From Us?

#1. High purity:

Our purity is as pure as 99%, suitable for compounding for your dogs or cats.

#2. Low MOQ:

Our MOQ starts from 50G. For us, there is no business too small.

#3. Fast and safe shipping:

We make sure you can get it safely, also tracking can be provided within 3~4 days.

#4. Reasonable prices:

If you compare our prices with other suppliers, you will find our offer is quite reasonable for 99% type.

What Is Trilostane (Vetoryl)?

Trilostane Chemical Structure

Cas Number: 13647-35-3

Molecular Formula: C20H27NO3

Molecular Weight: 329.433 g/mol

HS code for pure powder: 2937290090

Trilostane is a white to off-white crystalline powder, marketed under Vetoryl for veterinary uses.

It is soluble in DMSO and DMF but difficult to be dissolved in water, with a solubility at 20°C is of about 59.3mg/l.

It used to be approved for the treatment of Cushing’s syndrome for humans until it was withdrawn in 1994 from the USA.

Currently, it is mainly used for Cushing’s in dogs and cats (pituitary-dependent hyperadrenocorticism and adrenal-dependent hyperadrenocorticism).

It was also used for breast cancer in the UK.

Some compounding pharmacies also have it compounded for the skin disorder Alopecia X for dogs.

Please note that it is not allowed to give pets trilostane with hepatic or renal diseases.

Avoid using it simultaneously with other drugs such as mitotane and ketoconazole that suppress adrenal activities.

What Are Trilostane Side effects?

Trilostane is a fast-acting agent with very few side effects.

It is well-tolerated for most cats and dogs, but you need to watch your pets closely after they are medicated.

Side effects include but are not limited to: loss of appetite, vomiting, diarrhea, lethargy, unstable walking, weakness, heavy panting, muscle pain, and excessive drooling.

You can try to avoid those side effects from the start by using smaller dosing than recommended dosages and later increase the dosing slowly to recommended dosages.

In case of serious conditions such as non-stopping vomiting, or choking, contact your veterinarian immediately.

How To Feed Trilostane To Cats And Dogs?

When our dogs or cats are sick and need to take trilostane for their sufferings, how do feed them?

#1. How to feed

Due to the primary side effect of losing appetite, it is recommended to stash the capsule into their favorite foods, but do not give them too much, as they may throw up later from being too full.

Try to give them the medication on a routine schedule, once daily, at the same time of the day, and preferably in the morning with an empty stomach.

When you are stashing the branded capsules or compounded ones, make sure you are wearing disposable gloves for protection.

If you do not have any gloves around, make sure you wash your handly thoroughly after handling them.

Take extra caution especially are you planning to be pregnant.

Do not break a capsule to make up for proper dosing.

#2. Daily dosage

To prevent possible side effects, your veterinarian would advise you to start with the lowest dosing according to body weight.

The treatment dosing of hyperadrenocorticism for dogs is 2.2mg~ 6.6mg/kg. There are capsules of 5mg, 10mg, 30mg, 60mg, and 120mg available, make your combination after your calculation.

After 10-14 days of medication, take your pets to your veterinarian for a re-examination, no matter whether it is good or bad. Follow your vet’s advice on how to proceed further.

Quality Standards

trilostane powder quality standards

As you can see from our quality standards above, we have strict quality control over impurities.

Our single impurities are controlled under 0.5%, and total impurities are less than 1.0%.

Now check our correspondent testing results: 0.1% and 0.03%.

This should be the best quality in China.

Also, we keep our assay over 99% and make it as potent as possible.

How Much Does Trilostane Cost?

If you are looking to buy pure powder of 99% type for compounding, for your dogs or cats, or horses, please check our offers as below:

For 50g, our price is about 500usd.

For 500g, our cost is around 2000usd.

1kg our price is 3000usd for your ref.

Please note that our prices are subject to raw material fluctuations.

Since you have seen our prices, now please check trilostane prices from other online suppliers so you know where to buy them.

cost from MCE is 190usd for 200mg

price from scbt is 1170usd for 100mg

price from sigma is 436usd for 50mg

price from TRC-canada is 600usd for 100mg

As you can see from the prices from other suppliers, the best offer you can get is 190usd for 200mg.

The highest offer is from scbt, 1170usd for 100mg.

If you only need several grams of it for research, you are welcome to contact us any time.

If you are a pharmacist looking for 99% powder for your compounding, we promise you the best price with the highest quality in Asia.

How To Store Trilostane Powder?

In case you have bought or imported more powder than you can use for one compounding or production, you will need to store them for future use, how you should store them to keep them fresh as a new batch?

Below is how:

Make sure your powder is packed in an air-tight, well-sealed foil bag, protected from heat, moisture, and light.

If you have vacuum packing equipment, it can not be better with vacuum packing.

The shelf life for the pure powder is at least 2 years at a room temperature of 25°C.

If the temperature is too high such as 35 or 40 degrees, it will make its shelf life shorter.

If it is stored in a freezer, its shelf life will be over 4 years.

No matter how long it has been stored, to make sure of its quality and medical efficacy, retest its purity by HPLC and structure by 1HNMR before you plan to use it again during storage.

Though it is sensitive to temperature fluctuations, a small and mild change is allowed for its storage (20°C~30°C).

As long as the temperature change is not dramatic, it will be fine.

Just make sure it is not 30°C in one minute and 20°C in another.

If you only have a small quantity of its powder, feel free to store it under -20°C in your refrigerator.

Seal it tightly to avoid any moisture.

Technical Documents Download

COA

MOA (Contact us directly for analysis method)

MSDS

References

  1. https://en.wikipedia.org/wiki/Trilostane
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Trilostane
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855282/
  4. https://www.drugs.com/vet/vetoryl-capsulestrilostane.html
  5. https://sitem.herts.ac.uk/aeru/vsdb/Reports/1891.htm

Other Veterinary APIs you may like