Buy 99% Tianeptine Sulfate API With Best Offers

Why You Should Import Tianeptine Sulfate Powder From Us?

#1. High Purity:

Our purity is 99% as min, check our COA below.

#2. low MOQ:

Our MOQ starts from 100G, repacking can be arranged within 1.5 Days.

#3. Short Lead time:

We have 25kg as running stock, repacking can be arranged rapidly and tracking will be provided to you within 3~4 days.

#4. Quality guarantee:

100% refund for any quality issues.

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What Is Tianeptine Sulfate?

tianeptine sulfate chemical structure

Cas number: 1224690-84-9

Molecular formula: C42H56Cl2N4O14S3

Molecular weight: 1008g/mol

Chemical name: 7-((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid compound with sulfuric acid (2:1) dihydrate

Other names: Tianeptine hemisulfate monohydrate, 1224690-84-9, Tianeptine hemisulfate monohydrate (THM), 7-((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid compound with sulfuric acid (2:1) dihydrate, Tianeptine sulphate, Tianeptine-d4.

Tianeptine Sulfate is a white to off-white crystalline powder mainly used for depression.

Sometimes it is used as nootropics along with its siblings: Tianeptine sodium and Tianeptine free acid. 

Because of the poor solubility of tianeptine acid in the water and its instability for storage, tianeptine acid is often made into sulfate salt or sodium salt for better and easier dosing.

How Is Tianeptine Sulfate Produced?

The synthesis of sulfate salt is pretty similar to the synthesis route of tianeptine sodium.

The only different step is the last, the salt formation step.

The sodium salt is made by adding an alkali solution of ethanol/NaOH, while the sulfate salt is made by adding a solution of H2SO4.

Due to a lower yield, sulfate salt will cost more than sodium salt.

The simple steps are as below:

#1. Adding a solution of sulfuric acid in a solvent comprising water alone or in combination with acetic acid.

#2. Crystallizing the sulfate salt.

If you have sodium salt on your hand, you can make it into free acid by adding an acetic acid solution.

Then you further make the acid into sulfate salt crystals.

Tianeptine Sulfate vs Free Acid

Tianeptine sulfate vs free acid

Speaking of tianeptine acid made into sulfate or sodium salt, let’s check out why and what the differences are between sulfate salt and free acid.

#1. Similar water solubility (insoluble in water)

Tianeptine sulfate is an organic salt while tianeptine acid is an organic acid.

Some people may suppose tianeptine sulfate salt should be very soluble in water as it is a salt, but this turns out to be the wrong conclusion.

According to our lab tests, at room temperature, Tianeptine Sulfate is soluble in dimethylformamide but insoluble in water or methylene chloride.

Tianeptine acid is Insoluble in water or methanol but slightly soluble in ethanol.

In a common sense salts should have better water solubility than acids at higher temperatures and solubility tests also prove this point.

#2. Stability

Tianeptine sulfate is a little more stable than tianeptine acid.

Sulfate salt has monohydrate within, so it is too sensitive when exposed to air for a little while.

Please note both of them are sensitive to light and you have to store them from light.

#3. Cost

The cost of tianeptine sulfate on the market is 20%~30% higher than that of free acid.

Free acid price is similar to sodium salt but slightly cheaper.

To be frank, free acid is the intermediate of sodium and sulfate salt.

Both sodium and sulfate salt are further processed from free acid.

Therefore, both sodium and sulfate are more expensive theoretically.

#4. Bioavailability

Sulfate salt has the best bioavailability among all the three, this is also why sulfate is the most popular product.

We are not sure whether free acid is allowed to be taken or prescribed by doctors or pharmacists.

There is no clinical research on the indications for free acid.

Take extra caution before you take any action.

Tianeptine Sulfate vs Sodium

As both sulfate and sodium are from the same tianeptine family you are wandering between sulfate salt and sodium.

Well, look no more my friend. 

We have discussed the 6 differences between tianeptine sulfate and tianeptine sodium in detail on our tianeptine sodium page.

You can click on the link above to check the details.

After you check all those differences, then you can decide which to choose.

Dosages

As tianeptine sulfate is not enlisted in any pharmacopeia, there are not any dosages from official sources such as Drug Evaluation websites from any country.

But still, we see tianeptine sulfate 25mg capsules and tablets on the market.

Wherever you see them, keep in mind that those dosages are not approved by any FDA.

Tianeptine sodium caps or tabs are just other stories, they are approved by officials of drug evaluation

Where To Buy Tianeptine Sulfate Online?

If you want to buy tianeptine sulfate for research, please contact us directly.

We have it in stock and ready for shipping.

Please check our prices below.

We will also give you some prices from other suppliers for your ref.

You can also download our COA below to check our quality standards first.

Currently, we are running 25kg in stock to keep it always fresh.

The price from octagonchem for commercial order quantities over 50kg is around 3500 USD/kg.

For quantities of 10kg or less, our cost is around 3600 USD/kg.

As all prices are subject to raw material price fluctuations, please contact us directly for more accurate prices.

But there are other places you can buy it online, please check local suppliers for your ref.

Cost from tianeptinedirect is 7000usd per 1kg
Tianeptinebuyonline is selling by 800usd per 100g
Unit price from tianeptinestore is 600usd per 50g
Price from savant-research is 106usd per 10g

After comparing all the offers from other vendors, you will find that the best offer you can get is 7000 USD for 1kilo.

Though they can ship directly from the US or Canada, our price difference is still huge.

As for the quality, we are sure our quality is second to none, which we are very proud to say loudly.

Anyway, if you are ready to order commercially, octagonchem should be your top choice.

Technical Documents Download

References

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