Buy Tianeptine Sodium In Stock of 25kg (2020.06.22)
Why you should buy tianeptine sodium from us?
High quality standards: our standard is EP9.0 with steady manufacuring process of high yields.
Quality guarantee: 100% refund for any quality issues after testing.
Samples for quality approval: we have samples for your quality approval, contact us anytime for a sample.
Fast shipment: goods will be shipped out after rapid repacking and tracking number will be provided to you within 3~4 days.
Low MOQ: for trial you can order 1KG, we also repack it to ship 500g and 100g as trial orders.
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What is Tianeptine Sodium?
Cas number: 30123-17-2
Molecular formula: C21H24ClN2NaO4S
Molecular weight: 458.9 g/mol
It is a white to yellowish hygroscopic powder. The color difference is partially caused by purity. When the purity is over 99%, it tends to be white rather than yellowish. As it is easily to absorb moistures in the air, it should be sealed properly against becoming rocks.
It has been used as an atypical antidepressant for the treatment of the major depressive disorders. It is also used to treat anxiety, asthma, and irritable bowel syndrome. It is one of our most competitive pharmaceutical ingredients in stock. It is marketed as Stablon and Coaxil in many countries.
Peolple also use it for treating pain caused by fibromyalgia because of its anticonvulsant and analgesic effects. It has been effective in the treatment of attention-deficit hyperactivity disorder with minimal side effects too.
Is Tianeptine sodium a Nootropic?
The answer is Yes.
Nootropics, also known as smart drugs, are used to improve cognitive function, particularly executive functions, memory, creativity, or motivation in healthy individuals.
Tianeptine is a TCA-like and serotonergic enhancing medication prescribed commonly in the Middle East and Europe for depression and anxiety. However, the study shows it does help to improve people’s cognitive functions.
The FDA hasn’t approved Tianeptine for any use in the United States for any conditions, let alone allow it to be used to improve cognitive functions.
Tianeptine Sodium vs Sulfate (6 main differences)
There are three commonly seen Tianeptine forms on the market: Tianeptine free acid, sodium salt, and tianeptine sulfate salt.
Among them, tianeptine acid is the least popular and cheapest type. Maybe tianeptine free acid only exists because it can be made into various tianeptine salts such as tianeptine hydrochloride, tianeptine tosylate, tianeptine phosphate, etc. So here we only list the difference between tianeptine sodium and tianeptine sulfate (also written as tianeptine sulphate).
1. Their age. (Sodium is older than sulfate)
Sodium tianeptine is the first to be widely used for medical purposes for depression since 1960. Tianeptine sulfate is later developed and improved versions to replace the sodium form.
2. Stability. (sulfate salt is more stable than sodium salt)
Both tianeptine sodium and sulphate are stable when protected from light and air. But sodium salt is very hygroscopic to get chunky. While tianeptine sulfate salt contains monohydrate with itself, it is more stable when exposed to air for a short period.
3. Water solubility uniformity. (Tianeptine sulfate has better uniformity than sodium)
In water solutions PH ranged 1~6, the soluble amount of tianeptine sulphae in water is very average. Its solubility curve is very smooth, the value gets slightly smaller as the PH goes up. While sodium salt has a sudden drop when PH goes from 1 to 6. As the stomach fluid PH ranges from 1.5~3.5 and sure you will choose sulphate to maintain a stable solubility.
4. Taste. (Tianeptine sulfate is not bitter, sodium is)
The bitterness of sodium tianeptine can linger in your mouth for one month if you take the API directly. While tianeptine sulphate is much better on the taste, no such strong bitterness at all.
That’s why you only see tianeptine sodium capsules but rarely see any tianeptine sodium tablets on the market.
5. Half-life and Bioavailability. (Tianeptine sulfate lasts longer than sodium)
According to researches and online reviews, tianeptine sulphate performs better on both half-life and bioavailability. Sulphate is easier to absorb and its effect lasts longer, while dosing sodium can go to 6~7 times daily to obtain the same effect as sulphate.
6. Price. (Tianeptine Sulfate is 20% higher than sodium)
As tianeptine sulfate has better performance almost on any aspect than tianeptine sodium and the production process is a little more complicated, its price is also a little higher, which does make sense.
Tianeptine vs Trazodone
Both Trazodone and Tianeptine can be used for the treatment of depression. What are their differences?
#1. Trazodone is an antidepressant agent. It affects chemicals in the brain that may be unbalanced in people with depression.
#2. Trazodone is mainly used to treat the major depressive disorder. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain.
#3. Trazodone has been approved for medical use in the United States in 1981, while Tianeptine has not been prescribed for any indications in the United States until today.
#4. Trazodone raw materials are cheaper. The cost of trazodone is about 1/7 of that of Tianeptine.
What are Tianeptine Sodium Side Effects?
Common side effects(>1% frequency)
Headache (up to 18%) / Dizziness (up to 10%) / Insomnia/nightmares (up to 20%) / Drowsiness (up to 10%) / Dry mouth (up to 20%) / Constipation (up to 15%) / Nausea / Abdominal pain / Weight gain (~3%) / Agitation / Anxiety / irritability
Uncommon side effects(0.1-1% frequency)
Bitter taste / Flatulence / Gastralgia / Blurred vision / Muscle aches / Premature ventricular contractions / Micturition disturbances / Palpitations
Orthostatic hypotension / Hot flushes / Tremor Rare (<0.1% frequency) / Hepatitis / Hypomania / Euphoria / ECG changes / Pruritus / allergic-type / skin reactions / Protracted muscle aches
Warnings (tianeptine sodium withdrawal)
According to tianeptine marketer Servier, stopping of treatment with tianeptine is difficult, due to the possibility of withdrawal symptoms in a person. The severity of the tianeptine withdrawal is dependent on the daily dose, with high doses being extremely difficult to quit. DEA states that the withdrawal symptoms in humans typically result in agitation, nausea, vomiting, tachycardia, hypertension, diarrhea, tremor, and diaphoresis.
Data are demonstrating that the abuse of tianeptine is increasing while contributing to the current opioid epidemic.
What is Tianeptine Sodium Price and where else to buy? (Last update 2020.02.28)
Currently we have it for sale and our running stock is 25kg to keep it always fresh.
The price from octagonchem for commercial order quantities of 50kg or more is around 2900USD/kg.
For quantities of 10kg, our cost is around 3000USD/kg.
As all prices are subject to the raw material price fluctuations, please contact us directly for more accurate prices.
For a better comparison, you check prices from other vendors for your ref.
Price from tianeptinedirect is 6500usd per kilo
price from tianeptinebuyonline is 800usd per 100g
price from tianeptinestore is 440usd per 50g
powder price from savant-research is 106usd per 10g
Where to buy tianeptine sodium online?
If you need to buy tianeptine sodium powder, Please contact us now for a quick order. We have 27.5KG Tianeptine Sodium pure powder In Stock Ready For Fast Shipping(2020.01.08).
You can check our terms below and prices from other suppliers above for your decision.
Standards: EP 9.0, 99% as min
Sample For Quality Approval: Available
Packing: 1kg/Bag or customized packing.
MOQ: 1KG (Subject To Negotiation)
Our tianeptine series will not be sold to individuals, only to companies or institutions used for research only.