99% Tadalafil API Powder Manufacturer In China

Looking For The Largest Tadalafil Manufacturers In China?
Contact Us Now!

Why You Should Import Tadalafil Powder From Us

#1. WE GUARANTEE SAFE DELIVERY BY ABLE AGENTS OR A 100% REFUND.

#2. High purity:

our purity is 99% as min with USP standards

#3. Quality guarantee:

we have a full refund policy for any quality issues.

#4. Low MOQ:

Our MOQ starts at 100G

#5. Samples for quality approval are available:

Contact us for a sample directly!

#6. Short Lead time:

A tracking number will be provided within 3~4 days after your order.

What Is Tadalafil?

tadalafil structure

Cas number: 171596-29-5

Molecular formula: C22H19N3O4

Molecular Weight: 389.4 g/mol

Chemical Name: (2R,8R)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

HS Code: 2934999099(Other heterocyclic compounds-其他杂环化合物)

Tadalafil is the active ingredient in the famous Cialis.

Cialis was approved as a generic by USFDA in 2003.

Tadalafil is freely soluble in dimethyl sulfoxide(DMSO), slightly soluble in methylene chloride, and practically insoluble in water.

The pure form appears as a clear crystal or white crystalline powder.

Currently, people widely use it for erectile dysfunction next to sildenafil citrate (Viagra) and avanafil (Stendra or Spedra).

Cialis is the most famous finished formulation brand and, of course, is the most expensive one.

There are tons of cheap generic formulations out there for you if you check them out in India.

Tadalafil was first developed by the pharmaceutical company Eli Lilly and Company and was patented in 1996.

The patent for tadalafil expired in the United States in 2017, which allowed other pharmaceutical companies to manufacture and sell generic versions of the drug.

The main mechanism of action of tadalafil is to inhibit the activity of PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP).

cGMP is a chemical messenger that relaxes smooth muscle cells and increases blood flow to the penis, which is necessary for achieving and maintaining an erection.

By inhibiting PDE5, tadalafil helps to increase the levels of cGMP in the body, which can improve erectile function in men with ED.

Tadalafil is available in a number of dosage strengths, including 2.5 mg, 5 mg, 10 mg, and 20 mg tablets.

It is typically taken as needed, about 30 minutes to an hour before sexual activity.

The recommended starting dose is 10 mg, but the dosage may be adjusted based on the individual’s response to treatment and other factors such as age and medical history.

What Is Tadalafil Used For?

Tadalafil is a medication that belongs to the class of drugs known as phosphodiesterase type 5 inhibitors.

It is primarily used to treat erectile dysfunction (ED) and symptoms of benign prostatic hyperplasia (BPH).

ED is a condition in which a man is unable to achieve or maintain an erection sufficient for sexual activity.

Tadalafil works by relaxing the muscles in the blood vessels of the penis, allowing blood to flow more easily and causing an erection.

BPH is a condition in which the prostate gland becomes enlarged and causes urinary symptoms such as frequent urination, weak urine flow, and difficulty starting and stopping urination.

Tadalafil can also help to relieve these symptoms by relaxing the muscles in the prostate and bladder.

Tadalafil can be taken either as needed or daily at a lower dose.

When taken as needed, the recommended starting dose is 10 mg, which can be adjusted based on the individual’s response and tolerability.

When taken daily, the recommended starting dose is 2.5 mg, which can also be adjusted as needed.

Tadalafil is usually well-tolerated, but it can cause side effects like all medications.

The most common side effects are headache, back pain, muscle aches, and indigestion.

These side effects usually go away after a few hours. More serious side effects are rare but can include an allergic reaction, vision changes, and prolonged erection.

It is important to consult a healthcare provider if any of these side effects occur.

Tadalafil should not be taken with certain medications, such as nitrates, because it can cause a dangerous drop in blood pressure.

It is also essential to inform the healthcare provider of any other medications being taken, as tadalafil can interact with certain medications and cause serious side effects.

Tadalafil vs Sildenafil

tadalafil vs sildenafil

Those two are the top 2 most popular meds used for ED:

both of them are generics;

not controlled substances;

both are not cheap in finished dosages while relative APIs are not expensive at all.

But they have their differences.

Below we list their main differences for your ref.

#1. Indications

Cialis is indicated for erectile dysfunction (ED) and benign prostatic hyperplasia.

Viagra is indicated for ED, pulmonary arterial hypertension, and sexual dysfunction.

#2. Half-life

The half-life of Cialis is 17.5 hours and Viagra only has 4 hours.

When used for ED, Cialis can last as long as 36 hours while Viagra only lasts about 6 hours.

Because of Viagra’s shorter half time, it takes less time for Viagra to work (about 1 hour after taking), while Cialis would need 2 hours to work.

#3. Dosage forms

Cialis has 2 dosage forms: oral tablets and Compounded Oral Suspensions.

Viagra has 3 dosage forms: oral tablets, Compounded Oral Suspensions, and intravenous solutions.

#4. Cost

As a pharmaceutical raw material supplier in China, we are quite familiar with the cost difference between Cialis and Viagra raw materials as pure powder.

The cost of active ingredients in Cialis is about 4 times that of Viagra.

We have listed our tadalafil prices below in detail for your ref.

As for the formulation prices, different brands have different price tags.

The most expensive one should be Cialis from Eli Lilly, a 10mg pill that cost about 30~45usd per unit in 2015.

The current price is about 15usd per 10mg-tablet.

If you go to a compounding pharmacy, I think the price there should be much lower.

How Much Does Tadalafil Powder Cost?

For pure powder of USP/EP standards, our price is about 380usd/kg for commercial order quantities.

Some people may want an all-natural type.

To be frank, there is no such thing called all-natural.

All the pure powders you can find on the market are 100% synthesized in large factories.

Maybe you are talking about is yohimbine HCl, which is extracted from plants and costs more than 1000usd per kg.

If you need to buy it online for research, please contact us directly.

Our samples are available for quality testing, just fill in our sample form so we can proceed.

Techinical Documents Download

References

Disclaimer

Our pure powder is used for research purposes only, not intended for human use in any way.

Other Molecules You May Need