98% Lubiprostone API With Best Offer

Why You Select Us As Your Lubiprostone Supplier

#1. High purity:

We have strict control over the purity and we keep the purity over 99% and single impurity less than 0.1%

#2. Fast shipment:

The package will be sent out to you within 3~4 days after your order confirmation by FedEx.

#3. Low MOQ:

If you don’t have a sufficient budget for research, it is cool.

You can order 1G to start. If 1G is still too much as a trial order, 0.5G is also ok for us.

Looking For Leading Lubiprostone Manufacturer In China? Contact Us Now!

What is Lubiprostone?

Lubiprostone chemical structure

Cas number: 333963-40-9 (136790-76-6)

Molecular formula: C20H32F2O5

Molecular weight: 390.46 g/mol

Chemical Name: 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid

HS Code: 2937500000(Categorized as prostaglandins, thromboxanes, and leukotrienes 归类到前列腺素、血栓烷和白细胞三烯

Lubiprostone is a white to off-white crystalline powder with a specific optical rotation between -42° and -48°.

It is very soluble in ether and ethanol but insoluble in water.

It is one of the most popular prostaglandins in the market along with alprostadil, latanoprost.

Prostaglandins are an important class of endogenous natural products that have multiple biological activities. 

What Is Lubiprostone Used For?

Lubiprostone was the first chemical-based constipation treatment approved for marketing by the U.S. Food and Drug Administration (FDA).

Even today, it is the only prescription drug approved for the treatment of long-term chronic idiopathic constipation in Switzerland.

Lubiprostone is a chloride channel activator that selectively activates type 2 chloride channels (ClC-2) located in the luminal cell membrane of the epithelial tip of the gastrointestinal tract.

Increasing the secretion of intestinal fluid and intestinal motility thereby improves bowel movements and alleviates the symptoms of chronic idiopathic constipation without altering the plasma concentrations of sodium and potassium.

Compared to other laxatives, it not only shows better treatment effects but also has a lower chance of resistance to long-term application with the advantage of a small dose.

With low toxicity to the human body, it exerts various physiological effects in a good way when you even take a small amount.

Therefore, it has attracted a lot of interest and attention in the pharmaceutical and medical industry.

How Much Does Lubiprostone API Cost?

If you are a scholar doing research, our price for an order of grams is around 800~1000 USD/G.

You can also check the prices from reagent companies such as Sigma, scbt, or trc-Canada.

On their websites, you can see that the price from Sigma is around 700 USD per 50mg.

The unit price from scbt is 300 USD per 1mg.

By comparison, you can see that if you need less than 100mg for your research, your local reagent company will be your top choice.

When you need more than 100mg, you may consider us as your vendor, you can at least have a better price.

If you need it in commercial order quantities, say 50~500 Grams, our total price including shipping cost by courier is about 500usd~600 USD per gram.

Anyway, whatever quantity you may need, you can contact us directly for cost and inventory details for comparison.

When you are ready to order, you can contact us anytime.

Manufacturer Documents Download

COA (Certificate of Analysis)

MOA (Method of analysis)

MSDS (Material Safety Data Sheet)


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