Buy 99% Emeramide(NBMI)
Why You Should Buy Emeramide Powder From Us?
#1. Consistent Quality:
The bulk powder has a purity of 99% as min and impurities are controlled below 0.5% for every batch. We have 1HNMR and HPLC spectrum for quality proof.
#2. Safe Delivery Channel:
Customers are happy to receive chemicals safely in their hands through our safe delivery channel.
( 2020.11.18 Currently there is not much stock, order it before it is sold out)
(2021.07.27 250G in stock)
Looking For Emeramide Manufacturers In China? Contact Us Now!
What is Emeramide? (Irminix)
Cas number: 351994-94-0
Molecular Weight: 284.4g/mol
Molecular Formula: C12H16N2O2S2
Emeramide is a white to off-white solid synthesized in the lab, also known as BDTH2, NBMI or [N1, N3-Bis-(2-Mercaptoethyl) Isophthalamide] .
It is one of our recently developed novel active melocules, a brand-new lipid-soluble antioxidant and a novel heavy metal chelator (Mainly used for mercury poisoning).
The chemical structure is specifically designed to bind mercury(II) in water.
Due to the small demand from the current market, we are still not producing it commercially till today.
It is insoluble in water but easily soluble in fat or lipids. It is also soluble in DMSO(DMSO is the solvent for its 1HNMR testing).
Emeramide was previously used for treating mercury contaminated soil and water, but later it is also found to be able to detox animals with mercury poisoning.
It is the most well-known reagent so far used for precipitation of mercury from water.
The precipiate of BDT-Hg or NBMI-Hg is so stable that it will suck and capture almost all mercury in water, even though mercury concentration level in aqueous solutions is very low.
What makes BDTH2 better is that BDTH2 will still be binding mercury even after it is oxidized into disulfide.
It will work in all sorts of water solutions, no matter what the PH is: acidic, basic, or neutral.
What Heavy Metals Can Emeramide Chelate?
Except the notorious mercury, BDTH2 is also proved to be effective on precipitating other divalent metals in water such as copper, lead, arsenic, selenium, cadmium, etc.
Scientific studies show that emeramide is able to chelate mercury, lead, cadmium, copper, manganese, zinc, iron across blood-brain barrier.
Mercury (Hg), especially from the groundwater, goal ore, wastewater of battery-recycling plants, coal tailings, and contaminated soil can be effectively chelated so the water can be cleaned.
What Are The Symptoms of Heavy Metal Poisoning?
There are two types of heavy metal poisoning, acute and chronic poisoning.
What we are talking about here is chronic poisoning by heavy metals.
We can find heavy metals everywhere, in the water, air, foods, and toys, etc.
If you live in a heavy metal polluted environment for a while, there are risks that you may get heavy metal poisoning.
Common symptoms of heavy metal poisoning include nausea, vomiting, shortness of breath, diarrhea, abdominal pain, tingling of your hands and feet, chills, and weakness.
It is better to see a doctor right away when you have these symptoms when you have lived in such environments polluted by high-level heavy metals.
How Is Emeramide Produced In Lab?
The synthesis of NBMI can be done in one-step synthesis as shown on the left. Just make sure the reaction takes place at a low termerature.
We first dissolve 2-aminoethylthiol hydrochloride in chloroform and triethylamine and placed in an ice bath with stirring.
Then we add the solution containing Isophthaloyl chloride dissolved in chloroform slowly.
Then we stir the mixture flask in an ice bath for two hours.
NBMI will precipiate after we add about 100 mL of 0.1 mol L−1 HCl.
Later we collect the and dry the powder to get what we need.
It was designated as an orphan drug by the European Commission and USFDA since 2012.
For now, it is still under processing by the pharmaceutical company EmeraMed Limited with the trade name as Irminix.
Currently, the drug developing company can offer a 14-day treatment x 300mg per day of Irminix®.
For more details, please check the web of EmeraMed Limited.
How Does Emeramide Work In Vivo?
Toxicity of mercury occurs at the intracellular level by binding of Hg2+ with thiol groups of relevant proteins.
It has been proved in amimal models that mercury toxicity can be relieved by the use of BDTH2, which is able to cross the cell membrane and the blood brain barriers to chelate Hg2+.
Also in clinical trial tests performed by Emeramed Limited, BDTH2 is proved to be a safe, effective way to detox mercury without the issues and side effects of other chelating agents.
In-vivo research (300mg per day) shows that it captures mercury and other heavy metals, which helps create free radicals and thereby restores normal functions to the mitochondria and overall health.
There is no known toxicity shown by clinical research so far.
It has been sold as a nutritional supplement under trade name of OSR-1 for many years.
With the trade name of Irminix, it has already been approved by the European Medicines Agency.
What Is the HS Code For Emeramide?
It is classified as an organic compound belonging to the class of Other organic sulfur compounds.
It has the HS code as 2930909099 in China Customs in 2021.
If you are looking to import its finished formulations, its HS code should be 30049092 or 3004900000.
Check with your customs broker before you import.
How Much Does Emeramide Powder Cost??
The price not only depends on your order quantity, but also is subject to upper-stream raw material price fluctuations.
If you need to buy a few grams for lab research, you can compare our prices with costs from other companies first.
For order quantity of 100G~500G, the cost from octagonchem is around 20usd/G
Now please check costs from reagent companies below and you will find the best price you can get from reagent company is 70usd/g for 5g.
Price from TRC-canada is 70usd/g for 5g
Price from medchemexpress is 180usd for 0.5g
Price from adooq is 60usd for 0.1g
Our Unique Selling Point
#1. High purity:
Our BDTH2 is 99% with consistent manufacturing process.
#2. Fast shipment:
We keep fresh stock of 200G~500G and international tracking number by TNT/FedEx can be provided within 3~4 days.
#3. Quality assurance:
100% refund for any quality issues tested with 1HNMR and LC-MS.
#4. Low MOQ:
Our moq starts at 10grams and subject to negotiation on smaller packings.
#5. Samples available for quality approval:
Samples for testing are available. (We may have to charge you sample fees as it is expensive)
#6. Commercial manufacturing status very promising and optimized:
we are ready to move to commercial-scale production from our current lab-pilot scale.
How To Ship and Store Emeramide Powder？
As a pure powder, it is white and almost odorless.
When there is color change or odor, test it for possible going-bad.
While it is a non-hazardous chemical to be shipped by air, courier, or by sea.
It is not a dangerous chemical, not toxic, not flammable or explosive, or oxidative.
It is actually very stable if you seal it and protect from light, moisture, or heat.
For the international shipping we can ship it under room temperature, no need to ice it to keep it cool.
From the shipping experiences of the past 2 years, it is stable after shipment in normal temperature, no obvious impurities found by HPLC after our customers got it.
While after you receive the package, it is highly recommended to be stored under -20 degrees celsius for long-term storage.
For short-term storage of several days or weeks, 2~8 degrees celsius will be just fine. Just make sure it is air-tight and protected from light and heat.