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Why You Should Order Alfacalcidol From Us?

#1. High purity:

Our quality standards are 98% as min, actual testing results are over 99% for every batch.

#2. Steady manufacturing process:

Our production processing has been stable as revised and improved over 3 times.

Quality and yield have been very stable after our last improvement.

#3. Competitive prices:

For 99% type pure powder, our offers are very competitive compared to other sources.

#4. Fast shipment:

Once your order is under processing, the tracking number will be provided within 3~4 days.

What is alfacalcidol?

alfacalcidol chemical structure

Cas Number: 41294-56-8

Molecular Formula: C27H44O2

Molecular Weight: 400.6 g/mol

HS Code: 2936290090

Alfacalcidol is one of the Vitamin D analogs and metabolites commonly prescribed for patients with kidney disease.

It is the middle form of vitamin d to be further transformed into our final physiologically active metabolite: calcitriol.

In order for vitamin d3 to be transformed into alfacalcidol, your kidney must function well.

Or vitamin d3 taken by you will not be absorbed by your body eventually.

Alfacalcidol vs Calcitriol vs Vitamin D2 vs Vitamin D3

alfacalcidol chemical structure

Alfacalcidol

calcitriol chemical structure

Calcitriol

There are so many vitamin D analogs as to 20 types that a lot of people are confused with which is which.

Alfacalcidol, calcitriol, vitamin d2, and vitamin d3 are the 4 most commonly seen Vitamin Ds in our daily lives.

You can see from their chemical structures above that they are very similar.

Vitamin d2 and d3 have one hydroxyl Group, alfacalcidol has two, and calcitriol has three.

That hydroxyl group is added step by step through our organs.

We see them in healthcare products, and gummies, we also see them as medicines.

What you may not know is how they are turned into each other and how they are related to each other.

Below we draw their route of metabolism for your ref.

Vitamin D2 is Ergocalciferol and vitamin D3 is cholecalciferol.

Both of them only have one hydroxyl group.

However, neither vitamin D2 nor vitamin D3 is physiologically active.

It takes two conversions in liver and kidney cells to get the active vitamin-d form to absorb calcium and phosphorus in the small intestine.

Vitamin d2 and d3 are firstly turned into alfacalcidol through the liver, then transformed into calcitriol by the kidney.

The healthy status of the liver and kidney will decide which of the 4 vitamin-d supplements you should take.

If you have a healthy liver and liver, take vitamin d2 or d3, either is ok, but vitamin d3 is more cost-effective.

For patients with liver diseases, orally taken vitamin d2 or d3 can not be turned into alfacalcidol, which means oral vitamin d supplements can not be absorbed by those people.

They have to take alfacalcidol or calcitriol directly.

Patients with liver and kidney diseases have to take calcitriol only.

If they try to take alfacalcidol, it will not be properly processed by the kidney into calcitriol.

Their differences between the four in general:

#1. Vitamin D2 and D3 are not physiologically active:

They have to be turned into the final active calcitriol to take effect.

Alfacalcidiol and calcitriol are metabolites of vitamin d3, not d2.

#2. Cost sequence:

calcitriol>alfacalcidol>vitamin d2>vitamin d3

How Much Does Bulk Alfacalcidol Powder Cost?

For small quantities of 99% type pure powder, our price is around 900USD per Gram.

If you need to buy it in commercial quantities such as kilos, the cost is around 400USD ger gram.

If you need its pure powder for research, you can check its prices from reagent companies for your ref below.

As you can see those 3 prices from the above, the best price you can get is 2600USD for 500mg.

If you need it for research, you can contact us for a change.

We provide you with higher purity yet with lower costs.

You find us, you find a solution when you have a limited budget.

Technical Documents Download

References

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