99% Alprostadil API Of ISO Factory

Why Choose Us As Your Alprostadil API Supplier?

#1. High purity:

Our purity by HPLC is 98% as min, testing value is 99% due to our optimal synthesis route.

#2. Low MOQ:

OCTAGONCHEM is a supplier that has a MOQ of 1G, packed in a small air-tight amber bottle.

#3. Prompt shipment with steady stock:

We keep fresh running stock for it, stock quantity is around 50G.

The tracking number can be provided to you within 3~4 days after your order.

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Contact Us Now!

What Is Alprostadil?

Alprostadil 745-65-3 (Prostaglandin E1) Chemical structure
Alprostadil Chemical Structure

Cas Number: 745-65-3

Molecular Formula: C20H34O5

Molecular Weight: 354.487 g/mol

HS Code: 2937500000

Alprostadil, also known as Prostaglandin E1(PGE1), is a white to slightly yellowish powder used for heart diseases.

It is one of our most expensive pharmaceutical ingredients sold by the Gram along with Vitamin D derivatives.

It is used to open the ductus arteriosus to carry out heart surgery.

What Is Alprostadil Used For?

Alprostadil is a naturally occurring prostaglandin.

It is used as a pharmaceutical ingredient in many formulations, such as creams, injections, etc, but mainly exists as injections.

#1. In babies with congenital heart defects.

It is used by slow injection into a vein to open the ductus arteriosus until surgery can be carried out.

It will cause vasodilation through a direct effect on vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth.

This is because, as a form of prostaglandin E (PGE1), it has multiple effects on blood flow.

It results in increased pulmonary or systemic blood flow in infants.

#2. For cyanotic congenital heart disease.

Its actions result in increased oxygen supply to the tissues to relieve heart conditions.

#3. In infants with an interrupted aortic arch or very severe aortic coarctation.

It maintains distal aortic perfusion by permitting blood flow through the DA from the pulmonary artery to the aorta.

#4. In infants with aortic coarctation.

It reduces aortic obstruction either by relaxing ductus tissue in the aortic wall or by increasing the effective aortic diameter by dilating the DA.

#5. In infants with these aortic arch anomalies.

Systemic blood flow to the lower body is increased, improving the tissue oxygen supply and renal perfusion.

#6. By injection into the penis or placement in the urethra.

It is used to treat erectile dysfunction.

It makes the penis swell, elongate, and get rigid when arterial blood rapidly flows into the corpus cavernosum to expand the lacunar spaces.

The entrapped blood reduces the venous blood outflow as sinusoids compress against the tunica albuginea.

While administered by intracavernosal injection or as an intraurethral suppository, alprostadil acts locally to relax the trabecular smooth muscle of the corpora cavernosa and the cavernosal arteries.

How Much Does Alprostadil API Cost?

First thing first, our pure powder of PGE1 is used for research only, not for human injections.

Our alprostadil is manufactured in a lab and used as a Reference Substance or Working Standard only.

There are only 4 GMP-approved manufacturers in China for it, but none of them is exporting it.

Any importers may try to contact Jilin Yinglian Bio if they only need a GMP source.

But prices from GMP factories are much higher, we just give you a little hint.

For commercial order quantities without GMP, such as 100G or 500G, our price from China is around 600 USD/G.

If you only need several grams, our cost is around 950 USD/G with shipping cost by courier.

But you are a researcher and you need to check the prices from reagent companies, such as Sigma, and SCBT, you will see that their prices are around 200 USD/10mg

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References

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