Polymyxin B Sulphate Structure

USDMF: Available

Standards: USP41

Sample For Quality Approval: Available

Packing: 1kg/tin (standard)

MOQ: 1kg as Standard Packing (Subject To Negotiation)

Leadtime: Contact Us Before Order

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What Is Polymyxin B Sulphate?

Pure Polymyxin B Sulfate powder is a white to off-white powder derived from the bacterium Bacillus polymyxa. It is one of our strategic active pharmaceutical ingredients for dermal ointments.

There are two types of Polymyxins: Polymyxin B and Polymyxin E(also known as colistin). Polymyxin B is composed of polymyxins B1, B1-I, B2, B3, and B6. Polymyxins B1 and B2 are considered major components. These related components are structurally identical except for a different fatty acid group on each fraction. Results from in vitro studies have shown marginal differences in MIC data when comparing the fractions.

Mechanism of Polymyxin B’s Bactericidal Effects is as below: Polymyxin B binds to the cell membrane and alters its structure, making it more permeable. The resulting water uptake leads to cell death of bacteria. Polymyxin B is a cationic basic peptide that acts like detergent.

Polymyxin B can be used for urinary tract infections and meningitis as it exerts bactericidal effects against almost all Gram-negative bacilli except the Proteus and Neisseria genera. 

What Are polymyxin b dosages?

Polymyxin B dosages are as below:

Polymyxin B powder for injection

polymyxin b ear drops

polymyxin b cream

polymyxin b sulfate eye drops over the counter

Polymyxin B sulfate Injection

polymyxin b lyophilized powder for solution

Polymyxin B sulfate is also made into first kits and topical ointments combining with other ingredients such as combining bacitracin, bacitracin zinc , neomycin sulfate, lidocaine HCl, etc.

What Is polymyxin b Class?

Polymyxin b sulfate belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues. But it is also an antibiotic. In China it is classified as Other Antibiotics with HS Code as 2941909090 with supper class as Antibiotics.

What is Polymyxin B Price? (Last Update 2019.11.30)

Pharm-Grade Polymyxin B sulfate price for commercial order quantities is about 4800~5000usd/kg as Fob Shanghai/Beijing. This price is for micronized polymyxin b powder. Polymxin b plain powder should be cheaper.

For more accurate polymyxin b prices, please contact us directly.

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