99% L-Glutathione Reduced Of GMP Factory
Glutathione—often called the “master antioxidant”—is the active pharmaceutical ingredient behind countless health, wellness, and beauty formulations worldwide.
As a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine, Glutathione functions as the body’s primary intracellular antioxidant and detoxifying agent.
It is the endogenous antioxidant that neutralizes harmful free radicals, supports cellular and mitochondrial health across various tissues and organs, and plays a central role in immune function, detoxification, and cellular repair.
We don’t just supply Glutathione API. We deliver pharmaceutical-grade purity, documented regulatory compliance, supply chain reliability, and technical partnership that gives you a competitive edge in this rapidly growing market—whether you’re manufacturing pharmaceutical formulations, dietary supplements, cosmetics, or functional foods.
Why Import L-Glutathione Reduced From Us?
#1. High-Quality Guaranteed With GMP/ISO
Our Bulk L-glutathione is over 99%, as confirmed by HPLC and GMP/ISO certificates from the manufacturer.
Meanwhile, our quality remains consistently high from batch to batch, thanks to our optimized manufacturing process and standard operating procedures.
#2. Competitive prices with quick dispatch
With our extensive manufacturing capacity, we can lower production costs relative to our competitors and more easily differentiate our pricing.
Plus, we can prepare the goods for shipping within 2~3 days for quantities between 100G and 100 KG.
L-Glutathione Reduced Applications and Specifications
Pharmaceutical Applications
Glutathione API is widely used in clinical settings:
Primary Clinical Indications:
Hepatitis and liver diseases — treatment or adjuvant treatment
Hemolytic diseases — supporting red blood cell health
Heavy metal poisoning — chelation and detoxification
Keratitis, cataract, and retinal diseases — ophthalmic applications
Corneal membrane disease
Adjuvant therapy in oncology — reducing chemotherapy-related oxidative stress
Dietary Supplements
Glutathione is one of the most widely used ingredients in dietary supplements, driven by heightened health awareness and an aging global population:
Anti-aging supplements — supporting cellular health and longevity
Immune support formulations — enhancing immune function and resilience
Detoxification products — supporting the body’s natural detox pathways
Sports nutrition — reducing exercise-induced oxidative stress
Skin health supplements — promoting skin brightness and reducing pigmentation
Cosmetics and Personal Care
Glutathione is mainly used in skincare products:
Skin-brightening serums and creams — reducing melanin formation and pigmentation
Anti-aging formulations — preventing skin aging and protecting against environmental damage
Protective skincare — defending against oxidative damage from UV and pollution
Restorative creams — supporting skin barrier function and repair
Functional Foods and Beverages
Glutathione is increasingly incorporated into functional foods and beverages, with increasing demand from the food and beverage industries in both developed and developing economies:
Nutritional beverages
Functional food products
Flour products — as a reducing agent that shortens bread-making time by one-half to one-third
Product Name: Bulk L-Glutathione Reduced (L-Glutathione, glutathione)
Appearance: A white powder
Solubility: Soluble in water (50mg/ml)
Cas Number: 70-18-8
Molecular Formula: C10H17N3O6S
Molecular Weight: 307.33 g/mol
Chemical Name: (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
HS Code: 2930909099 (Other organic sulfur compounds-其他有机硫化合物)
Suitability to be shipped by air as common goods: suitable. It is safe to be shipped by air as common goods.
Grade: Pharma-Grade/Food-Grade
Purity or Assay: 99%
Standards: Current USP Standards
Manufacturer Certificates available: GMP/ISO
Supplier Documents Available: COA/MSDS
Supply Capability: 1000KG per month
MOQ: 100 g
Price Ideas In 2023: 500 USD/1KG for food-grade, 800 USD/1kg for pharma-grade (Contact us by WhatsApp for more updated prices)
Lead Time: 2~3 days for quantities less than 50KG, 1~2 days for orders less than 500 g.
Stock Status: Over 100KG
Shipping Temperature: Room temperature
Storage: 2~8 °C (long term)
Technical Data
Specific optical rotation: -15.5º~-17.5º
Clarity and color of solution: clear and colorless
Heavy metals: NMT10ppm
Arsenic: NMT2ppm
Iron: NMT10ppm
Sulfate: NMT300ppm
Ammonium: NMT200ppm
Cadmium: NMT1ppm
Lead: NMT3ppm
Mercury: NMT1ppm
Loss on drying: NMT0.5%
Residue on ignition: NMT1.0%
Microbial Tests:
Total plate counts: NMT1000cfu/g
Yeast & molds: NMT100cfu/g
Total coli forms: NMT100cfu/g
E. Coli: Negative
S. Aureus: Negative
Salmonella: Negative
Assay: 98.0%~101.0%
Why Choose Us As Your L-Glutathione Supplier?
Please get in touch with us if you want a free quote for a 99%-type pure L-glutathione reduced with cas 70-18-8 to produce cosmetics or nutritional supplements.
OCTAGONCHEM is one of China’s leading producers of L-glutathione reduction, with a running stock of over 100 KG and the most competitive prices.
People widely use reduced L-glutathione in cosmetics as a whitening agent.
It is also used in many nutritional supplements for its anti-inflammatory and pain-relieving functions.
Please message us directly if you need to test the quality with a sample. We offer free samples in quantities under 5 grams, available in 5G and 1G packaging sizes.
Before you ask us for a sample, please make sure:
1. You have a FedEx account for freight to collect, so that you can arrange a pick-up from our office address.
2. Packing materials needed: Certain countries require eco-friendly packing materials, and the exact amount of plastic to be labeled on the packaging. Please inform us in advance if you have these requirements.
2. Check that you are allowed to import L-glutathione-reduced products into your country and that you can handle the relevant Customs clearance.
For anything unclear, contact us anytime:)
FAQs About L-Glutathione Powder
What is Glutathione used for?
Glutathione—also known as Reduced L-Glutathione (GSH)—is a naturally occurring tripeptide and the body’s primary endogenous antioxidant. It is used as the active pharmaceutical ingredient in pharmaceutical formulations (for hepatitis, hemolytic diseases, heavy metal poisoning, and ophthalmic conditions), dietary supplements (for anti-aging, immune support, detoxification, and sports nutrition), cosmetics (for skin-brightening, anti-aging, and protective skincare), and functional foods.
What are the brand names for Glutathione?
Glutathione is the generic name for the active ingredient. It is also known by synonyms including L-Glutathione Reduced, GSH, γ-L-Glutamyl-L-cysteinyl-glycine, and Reduced Glutathione.
What purity level do you guarantee for Glutathione API?
We guarantee 98.0%–101.0% purity (HPLC-verified), meeting and exceeding USP and EP specifications. Heavy metals are strictly controlled at ≤10 ppm. Every batch is tested for identity, purity, heavy metals, microbial limits, and quality parameters in accordance with pharmaceutical industry standards.
What documentation do you provide with each order?
Every shipment includes a Certificate of Analysis (CoA), Method of Analysis (MOA), Material Safety Data Sheet (MSDS), and stability data. For regulatory submissions, we provide DMF access letters, CEP documentation, and complete manufacturing process documentation.
What is your minimum order quantity (MOQ)?
For commercial manufacturers, our MOQ is 1 kg, with volume discounts available for larger commercial orders. For R&D, analytical research, and compounding pharmacy applications, we offer smaller quantities.
Is your Glutathione API GMP-certified?
Yes. Our API is produced in facilities that adhere to strict current Good Manufacturing Practices (cGMP) for pharmaceutical ingredients and fully comply with ICH Q7 guidelines. We maintain DMF filings with regulatory authorities.
What is the mechanism of action of Glutathione?
Glutathione functions as the body’s primary endogenous antioxidant through multiple mechanisms: (1) neutralizing reactive oxygen species, including free radicals, peroxides, and lipid peroxides; (2) protecting sulfhydryl groups in proteins and enzymes from oxidation; (3) chelating and detoxifying heavy metals and environmental toxins; and (4) supporting immune function and reducing inflammation.
What is the difference between Reduced Glutathione (GSH) and Oxidized Glutathione (GSSG)?
Reduced Glutathione (GSH) is the biologically active form, with a free thiol -SH group that directly neutralizes free radicals. Oxidized Glutathione (GSSG) is formed when two GSH molecules are oxidized, forming a disulfide bond. The ratio of GSH to GSSG is a key indicator of cellular health. GSH is the leading product segment with approximately 62% market share.
What is the solubility and storage profile of Glutathione API?
Glutathione is a white to off-white crystalline powder that is soluble in water (50 mg/mL). It should be stored at 2–8°C (refrigerated) in a tightly closed container, protected from light and moisture. Shelf life is 2 years.
What is the regulatory status of Glutathione?
Glutathione is approved for use in pharmaceutical, nutraceutical, and cosmetic applications across multiple regions. It meets USP and EP specifications. The compounded form of Glutathione is currently under FDA review.
What are the key market trends for Glutathione?
Key trends include: increasing demand for Reduced Glutathione (62% market share); growing preference for naturally extracted Glutathione (57% revenue share); rapid expansion in Asia Pacific as the fastest-growing region; advances in biofermentation production technologies; rising consumer awareness of antioxidant health benefits; and expanding applications across pharmaceuticals, nutraceuticals, cosmetics, and functional foods.
What are the clinical applications of Glutathione?
Glutathione is used clinically for hepatitis and liver diseases, hemolytic diseases, heavy metal poisoning (chelating heavy metals, fluoride, and mustard gas), keratitis, cataracts, retinal diseases, corneal membrane disease, and as an adjuvant therapy in various conditions.
Can you supply Glutathione bulk powder for compounding pharmacy applications?
Yes. We supply Glutathione API in quantities suitable for compounding pharmacies. Our API can be used to formulate patient-specific doses and alternative dosage forms.
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