Source 99% Ergothioneine API of GMP Factory

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Ergothioneine Powder—often called the “longevity vitamin”—is the active ingredient behind a new generation of premium nutraceuticals, functional foods, and high-performance skincare.

로서 naturally occurring sulfur-containing amino acid and thiourea derivative of histidine, Ergothioneine has emerged as one of the most powerful and scientifically validated antioxidants available today.

Unlike conventional antioxidants that are rapidly excreted, Ergothioneine is selectively accumulated and retained in cells for months via its specific transporter, OCTN1, and concentrates in tissues with the highest oxidative stress exposure—including the liver, kidney, brain, bone marrow, and eyes.

We don’t just supply Ergothioneine Powder. We deliver pharmaceutical-grade purity, documented regulatory compliance, supply chain reliability, and technical partnership that give you a competitive edge in this rapidly growing specialty ingredient market—whether you’re developing premium dietary supplements, functional foods, advanced skincare, or pharmaceutical formulations.

왜 경쟁사보다 우리를 선택해야 할까요?

1. Pharmaceutical-Grade Purity

We deliver Ergothioneine Powder with ≥98.0% purity (HPLC-verified), 그리고≥99.0%–99.5% pharmaceutical-grade purity is available for premium formulations. Every batch undergoes rigorous quality control testing for identity, purity, specific rotation (≥+122°), heavy metals (≤10 ppm), microbial limits, and impurity profile. We maintain complete documentation of pharmacopeial and non-pharmacopeial impurities—a critical requirement for regulatory submissions.

2. GMP-Certified Manufacturing with Full Regulatory Support

Our manufacturing facilities operate under strict cGMP standards ~와 함께 ISO 인증. Production is carried out using controlled microbial fermentation ~에 따라 cGMP pharmaceutical standards, ensuring consistent quality, full traceability, and reliable large-scale supply. We provide comprehensive documentation for regulatory submissions:

분석 인증서(CoA) per ICH guidelines
Method of Analysis (MOA) documentation
물질안전보건자료(MSDS) in GHS format
안정성 데이터—accelerated and long-term
Complete impurity profile documentation
GMP 인증 from recognized regulatory authorities
HACCP, ISO, KOSHER, and FDA compliance documentation

3. Supply Chain Reliability at Scale

Scalable capacity—From gram-level samples to multi-ton commercial orders
Global logistics—Seamless shipping to the US, EU, Asia-Pacific, and beyond
Flexible packaging—1 kg/bag, 5 kg/bag, 25 kg/drum (customizable)
Inventory buffer—Large inventory maintained year-round
Rapid delivery—Samples shipped same day; bulk orders arranged within 72 hours
Competitive pricing—Cost advantages without compromising quality
Asia-Pacific production hub—Leveraging world-class manufacturing expertise in China

4. Technical Partnership for Formulation Success

The Ergothioneine market is expanding at a remarkable 28% CAGR. Success requires a partner who delivers more than just raw material. We help you win by providing:

Formulation optimization support for supplements, functional foods, and skincare
Regulatory guidance for FDA GRAS, novel food, and cosmetic registration
분석 방법 개발 support
Custom particle size specifications to meet your formulation needs
Customizable delivery systems for enhanced bioavailability
Expert technical support from formulation scientists
Dedicated account management with rapid response

5. Compounding Pharmacy and Research Solutions

Small-order flexibility—Custom quantities for compounding and R&D applications
Purity you can trust—High-grade ingredients minimize cross-contamination risks
Technical guidance—Expert advice on storage, processing, and formulation
Reference standard availability—For analytical method development and quality control

왜 에르고티오네인인가?

The OCTN-1 Transporter: Targeted Cellular Accumulation

Ergothioneine is not just another antioxidant that circulates in the bloodstream—it is actively transported into cells via the OCTN-1 transporter (ergothioneine transporter protein). This transporter is expressed at high levels in tissues with the greatest oxidative stress exposure—the liver, kidney, brain, bone marrow, and eyes. Once inside, Ergothioneine accumulates in the mitochondria and nucleus, protecting at the cellular level where damage is most critical.

Potent Free Radical Scavenging

Ergothioneine is a powerful scavenger of hydroxyl radicals (• OH), hypochlorous acid (HOCl), and other reactive oxygen species. It also functions as an inhibitor of iron- or copper-ion-dependent generation of OH from hydrogen peroxide (H₂O₂), preventing the formation of these damaging radicals in the first place.

NF-κB Inhibition and Anti-Inflammatory Action

Ergothioneine’s key anti-inflammatory mechanism involves inhibiting nuclear factor-kappa B (NF-κB) activation 그리고 interleukin-8 (IL-8) release in response to stimuli such as TNF-α and hydrogen peroxide. This makes it a powerful agent against chronic inflammation.

Anti-Aging and Skin Protection

에르고티오네인 suppresses MMP-1 (a collagen-degrading enzyme), activates the Nrf2 antioxidant-response pathway, 그리고 reversibly inhibits tyrosinase. These mechanisms combine to protect against photoaging, reduce hyperpigmentation, and maintain skin barrier integrity.

Neuroprotection and Cognitive Health

Ergothioneine reaches the brain and exerts beneficial effects, including neurogenesis and neuronal maturation, positioning it as a promising agent for cognitive health and the prevention of neurodegenerative diseases.

Mitochondrial Protection

By accumulating in mitochondria, Ergothioneine protects these energy-producing organelles from oxidative damage, supporting cellular energy metabolism and physiological resilience.

Ergothioneine Powder Applications and Specifications

제조업체 문서 다운로드

COA

USP-NF2024 분석 방법

MSDS (필요하시면 문의하세요)

조제 약국

귀하의 문제점 해결:

규정 준수: 당사의 에르고티오네인은 FDA 등록을 받았고, USP/PhEur 규정을 준수하며, 분석 인증서(CoA)를 받았습니다.
일관된 품질: 99.9% 순도, 배치 간 일관성으로 신뢰할 수 있는 환자 결과를 제공합니다.
사용자 정의: 분말 또는 액상 형태로 제공되며, 최소 주문 수량(MOQ)은 10g에서 100kg까지 다양합니다.

사용 사례:

신경 보호 보충제
만성 염증 치료법
IV 영양제 제형

화장품 제조업체

귀하의 문제점 해결:

효능 주장: 78%는 산화 스트레스를 감소시키는 효과가 임상적으로 입증되었습니다(노화와 관련됨).
제형 안정성: 비건, 비유전자변형, 세럼, 크림, 스프레이와 호환됩니다.
시장 차별화: "에르고티오네인 함유" 라벨을 사용하여 과학 중심의 브랜드로 자리매김하세요.

사용 사례:

노화 방지 세럼
자외선 차단제 부스터
시술 후 회복 크림

제품명: 99% Ergothioneine Powder (중국어:마노미치 야당)

모습: 흰색 결정성 분말

용해도: 물에 용해됨(10 mg/ml)

CAS 번호: 497-30-3

분자식: C9H15N3O2S

분자량: 229.30 g/mol

화학명: (2에스)-3-(2-설파닐리덴-1,3-디하이드로이미다졸-4-일)-2-(트리메틸아자니우밀)프로파노에이트

HS 코드: 2934999099 (기타 헤테로고리 화합물-其他杂环화합물)

Suitability for shipment by air/sea/rail as common goods: 적합합니다. 일반 물품처럼 항공 운송이 안전합니다.

등급: 제약 등급/식품 등급/화장품 등급

순도 또는 검정: 최소 99.0% (HPLC 측정)

표준: 엔터프라이즈

제조업체 문서 사용 가능: GMP/ISO/COA/MSDS/SDS

공급 능력: 월 1000KG 이상

최소주문수량: 1kg

Bulk Ergothioneine Updated Price Ideas: 최신 가격을 알아보려면 WhatsApp으로 문의하세요.

리드타임: 500KG 미만 수량의 경우 2~3일 소요

재고 현황: 1000kg 이상

배송 온도: 실온

저장: 실온

FAQs About Ergothioneine Bulk Powder

What is Ergothioneine Powder used for?

Ergothioneine Powder is a naturally occurring sulfur-containing amino acid and potent antioxidant used as the active ingredient in premium nutraceuticals (anti-aging, cognitive health, immune support supplements), functional foods, advanced skincare (anti-aging, skin-brightening, barrier repair), and pharmaceutical formulations. It is often called the “longevity vitamin” due to its unique cellular protective properties.

What are the brand names for Ergothioneine?

Ergothioneine is the generic name for the active ingredient. It is also known by synonyms including L-(+)-Ergothioneine, EGT, 2-Mercaptohistidine betaine, Thioneine, Phytothioneine, 그리고 Ergothionin. It is the key active ingredient in numerous branded nutraceutical and cosmetic products.

What purity level do you guarantee for Ergothioneine Powder?

We guarantee ≥98.0% purity (HPLC-verified), 와 함께 ≥99.0%–99.5% pharmaceutical-grade purity available for premium formulations. FDA GRAS notices have recognized purity levels of ≥99.9%. Every batch is tested for identity, purity, specific rotation (≥+122°), heavy metals (≤10 ppm), microbial limits, and quality parameters in accordance with USP, EP, and CP standards.

What documentation do you provide with each order?

Every shipment includes a Certificate of Analysis (CoA), Method of Analysis (MOA), Material Safety Data Sheet (MSDS), and stability data. For regulatory submissions, we provide complete manufacturing process documentation, quality certificates, and GMP documentation.

What is the recommended usage level of Ergothioneine?

Recommended usage levels vary by application: nutraceutical supplements typically contain 5–25 mg per serving; cosmetic formulations typically contain 0.1%–2.0%; functional foods follow GRAS-approved levels up to 150 mg/100 g for beverages and baked goods. The optimal concentration depends on the specific formulation and intended use.

What is the solubility and storage profile of Ergothioneine Powder?

Ergothioneine Powder is a white-to-off-white, water-soluble powder with a solubility of up to 10 mg/mL. It should be stored in cool, dry conditions in well-sealed containers, protected from light and moisture. It exhibits exceptional stability over a wide pH and thermal range, making it highly compatible with complex formulations. Shelf life is 2~3년 under appropriate storage conditions.

Is ergothioneine FDA-approved?

Ergothioneine has received FDA GRAS (Generally Recognized As Safe) recognition for use as a food ingredient. Multiple GRAS notices have been completed, including GRN 001270 (Gene III Biotechnology), GRN 001191 (Shanghai EGT Synbio), and GRN 734 (ErgoActive®). It is also approved for use in cosmetics across China, the US, and the EU, and as a novel food ingredient in the EU.

What makes Ergothioneine different from other antioxidants?

Unlike conventional antioxidants that are rapidly excreted, Ergothioneine is selectively accumulated and retained in cells for months via its specific transporter, OCTN1, and concentrates in mitochondria and the nucleus of high-stress tissues. It is also one of the few antioxidants that is non-irritating at cosmetic levels—”no acid chemistry, no retinoid-style turnover”.

Can you supply Ergothioneine Powder for compounding pharmacy applications?

Yes. We supply Ergothioneine Powder in quantities suitable for compounding pharmacies. Our powder can be used to formulate patient-specific nutraceutical and topical preparations.

What is your typical lead time?

Samples can be shipped on the same day. For bulk orders, logistics can be arranged within 72시간. For standard quantities, the typical lead time is 3–5 days from stock.