중국 cGMP 공장에서 생산된 99% SBECD
Betadex Sulfobutyl Ether Sodium—also known as SBECD, Sulfobutylether-β-cyclodextrin, 그리고 Captisol®—is the active excipient behind some of the most innovative injectable and parenteral drug formulations in modern medicine. As a highly water-soluble, anionic derivative of β-cyclodextrin produced by introducing sulfobutyl ether groups, SBECD has emerged as the preferred solubilizing excipient for parenteral drug delivery, with an unparalleled record of safety, efficacy, and regulatory acceptance.
SBECD is available in multiple grades:
Injectable Grade — for parenteral formulations, with strict endotoxin control (≤20 EU/g)
Pharmaceutical Grade (Oral) — for tablets, capsules, and oral liquids
Nutraceutical Grade — for dietary supplements and functional foods
화장품 등급 — for skincare and personal care formulations
Research Grade — for analytical and preclinical applications
왜 우리에게서 SBECD를 수입해야 합니까?
#1. 고품질:
We guarantee the quality of our SBECD through consistent manufacturing processes and strict quality control: we manufacture our Betadex Sulfobutyl Ether Sodium powder in a GMP-compliant factory. Our steady and innovative manufacturing process yields high-quality powder.
#2. 최소 주문 수량:
시험 주문을 위해 100g과 200g 패키지를 준비했습니다.
#3. 테스트 가능한 샘플:
저희 제품의 품질에 대해 확신이 없으시고 정식 주문 전에 샘플을 테스트해 보고 싶으시다면, 저희가 샘플을 준비해 드리겠습니다. 직접 문의해 주세요.
베타덱스 설포부틸 에테르 나트륨(SBECD)이란 무엇입니까?
이름: SBECD
CAS 번호: 182410-00-0
분자식: NA
분자량: 2242.0461 g/mol
HS 코드: 3505100000 (덱스트린 및 기타 변성 전분-糊精及其他改性淀粉)
다른 이름: b-사이클로덱스트린 설포부틸 에테르 나트륨염, β-사이클로덱스트린 설포부틸 에테르, 설포부틸화 베타-사이클로덱스트린 나트륨염, SBECD, sbebcd.
Bulk Betadex sulfobutyl ether sodium Powder 흰색 또는 미색의 결정성 분말입니다.
그것은 가장 중 하나입니다 인기 있는 부형제 ever used in our pharmaceutical industry, especially for injections.
비정질이고 흡습성이 있습니다.
물에는 잘 녹고, 메탄올에는 약간 녹지만 에탄올, 에틸 아세테이트, 디클로로메탄에는 녹지 않습니다.
Its solubility in 100ml water is more than 50g, the pH of its 30% water solution is 5.4~6.8.
이것은 개선된 버전입니다 하이드록시 베타-사이클로덱스트린, with better complexation performance but at a higher price.
SBECD는 무엇에 사용되나요?
설포부틸-β-사이클로덱스트린은 물에 대한 용해성이 더 좋은 음이온성 사이클로덱스트린 유도체입니다.
이는 많은 비공유 결합 복합체를 형성합니다. 아피스 (물에 녹지 않는) API 특성을 개선하고 최적화합니다.
The SBECD & Heparin complex exhibits biological activity similar to heparin but with lower nephrotoxicity, so SBECD is widely used as a high-end injection carrier.
SBECD will make APIs more stable and more readily soluble in water for injection. It will also lower their renal toxicity and reduce their chances of hemolysis.
또한 SBECD를 사용하여 API 냄새와 쓴맛을 덮는 동시에 활성 성분의 방출 속도를 제어합니다.
연구에 따르면 신규 API 중 약 40%가 물에 녹지 않고, 약 60%가 물에 잘 녹지 않는 것으로 나타났습니다.
Due to their poor water solubility, clinical trials of new drugs are less effective than expected.
This poor water solubility has significantly slowed the approval of these new molecules as new drugs.
Therefore, many pharmaceutical manufacturers have widely used Sulfobutyl-β-cyclodextrin sodium to improve the solubility of poorly water-soluble APIs, thereby enabling many new drugs to be approved.
When we mix docetaxel with sulfobutyl-β-cyclodextrin sodium at a molar ratio of 1:12, the solubility of docetaxel in water increases by about 800-fold, enabling the development of docetaxel water injections.
When we tested the water solubility of the complexed compound between sodium calycetin (Another API) and sulfobutyl-β-cyclodextrin sodium, we increased its water solubility by about 76-fold.
After we mix Amiodarone (API name) with sulfobutyl-β-cyclodextrin sodium at a molar ratio of 1:2, we increase the solubility of the complex in water by 195-fold.In In In
2020, we had COVID-19; 렘데시비르 is formulated as an injection by combining betadex sulfobutyl ether sodium.
이것은 훌륭한 주사제이기는 하지만, 어떤 제약회사도 이를 남용해서는 안 됩니다.
According to scientific research, the maximum daily dosing is 320 mg/kg.
SBECD 파우더를 어떻게 배송하고 보관하나요?
For shipping SBECD, you can ship it by sea if you purchase it in commercial order quantities.
우리는 귀하를 위해 택배나 항공편으로 소량을 배송해드릴 수 있습니다.
It is a very safe chemical suitable for air shipment. Its certificate of safe air transportation is available.
During the transport, you don’t need ice bags or cold-chain storage. It is stable at RT.
설포부틸-β-사이클로덱스트린은 기밀한 내부 포장재에 보관하고 빛으로부터 보호해야 합니다.
Because it is hygroscopic and readily draws moisture from the air, water can compromise its quality if it is not sealed well.
비교적 안정적이기는 하지만, 열과 빛으로부터 보호되는 단단한 용기에 보관하세요.
You can store it at room temperature, ensuring there is no significant temperature fluctuation.
유통기한은 2년입니다. 사용 전에 꼭 테스트해 보세요.
SBECD 비용은 얼마인가요?
If you need to buy its injection-grade pure powder in commercial order quantities to manufacture injections, our FOB Shanghai/Beijing price is around 350~500 USD/Kilo.
시험용으로 킬로그램 단위만 필요한 경우 가격은 킬로그램당 600달러 정도입니다.
실험실 연구나 테스트를 위해 몇 그램이 필요하시다면, 저희는 가장 낮은 가격으로 최고의 품질을 약속드립니다.
In case you are not sure if you are getting a reasonable price from us, you can check some of our online prices below:
As you can see from the reagent company’s offers, the price per 0.5g is higher than the cost of one kilo from us, not to mention the per-gram prices.
If your lab doesn’t have sufficient budget, give us a chance—you won’t regret it.