99% Oxidized Glutathione Bulk Powder of GMP Factory
Oxidized Glutathione Bulk Powder—also known as GSSG, Glutathione Disulfide, and L-Glutathione (Oxidized)—is the essential oxidized counterpart to reduced glutathione (GSH) in the body’s premier antioxidant system.
As the disulfide-bonded dimer formed when two molecules of reduced glutathione are oxidized, GSSG plays a critical, often underappreciated role in maintaining cellular redox homeostasis and supporting the body’s natural detoxification and repair mechanisms.
We don’t just supply Oxidized Glutathione Bulk Powder. We deliver pharmaceutical-grade purity, documented regulatory compliance, supply chain reliability, and technical partnership that give you a competitive edge in this specialized and growing market—whether you’re manufacturing pharmaceutical formulations, dietary supplements, advanced cosmetics, or research-grade biochemicals.
Why Choose Us As Your L-Glutathione Oxidized Supplier
1. Pharmaceutical-Grade Purity
We deliver Oxidized Glutathione Bulk Powder that meets and exceeds USP and EP specifications, with ≥98.0% purity (HPLC-verified) and ≥99.0% pharmaceutical-grade purity, available for premium formulations. Every batch undergoes rigorous quality control testing for identity, purity, specific optical rotation (-96° to -106°), heavy metals (≤20 ppm), loss on drying (≤8.0%), and microbial limits.
2. GMP-Certified Manufacturing with Full Regulatory Support
Our manufacturing facilities operate under strict cGMP conditions with ISO certification. We provide comprehensive documentation for regulatory submissions:
Certificate of Analysis (CoA) per ICH guidelines
Method of Analysis (MOA) documentation
Material Safety Data Sheet (MSDS) in GHS format
Stability data — accelerated and long-term
Complete impurity profile documentation
GMP certification from recognized regulatory authorities
3. Advanced Fermentation Production Technology
Our Oxidized Glutathione is produced through controlled microbial fermentation—the preferred method for producing high-purity, naturally derived GSSG. This advanced biotechnological approach ensures:
Exceptional purity and potency
Superior sustainability credentials
Full traceability — from fermentation to finished API
Batch-to-batch consistency — rigorous quality control at every stage
Elimination of unwanted impurities
4. Supply Chain Reliability at Scale
Scalable capacity — From gram-level samples to multi-ton commercial orders
Global logistics — Seamless shipping to the US, EU, Asia-Pacific, and beyond
Flexible packaging — 0.1kg, 0.5kg, 1 kg, 5 kg, 10 kg, 25 kg (customizable)
Large inventory — Maintained year-round to ensure rapid fulfillment
Rapid delivery — Samples shipped within 24 hours; bulk orders arranged within 72 hours
Competitive pricing — Cost advantages without compromising quality
5. Technical Partnership for Formulation Success
The GSSG market is expanding steadily at a 3.6% CAGR, with the broader glutathione market growing at 8.82%. Success requires a partner who delivers more than just raw material. We help you win by providing:
Formulation optimization support for pharmaceuticals, cosmetics, supplements, and research applications
Regulatory guidance for global submissions
Analytical method development support
Custom particle size specifications to meet your formulation needs
Expert technical support from formulation scientists
Dedicated account management with rapid response
6. Compounding Pharmacy and Research Solutions
Small-order flexibility — Custom quantities for compounding and R&D applications
Purity you can trust — High-grade ingredients minimize cross-contamination risks
Technical guidance — Expert advice on storage, processing, and formulation
Reference standard availability — For analytical method development and quality control
Bulk L-Glutathione Oxidized Powder Applications and Specifications
Manufacturer Documents Download
Pharmaceutical & Research Applications (Primary Growth Driver)
GSSG is widely utilized in research focused on antioxidant mechanisms, oxidative stress, and cellular protection. Key applications include:
Redox biology research — studying oxidative stress and cellular protection mechanisms
Proteomics — aiding in protein synthesis and cellular repairs
Drug development — enhancing bioavailability and stability of pharmaceutical formulations
Antiviral and antibacterial research — compositions with glutathione reductase show potential for pharmaceutical use
Diagnostic applications — enzymatic determination of NADP and NADPH
Oxidative stress biomarkers — measuring the GSH: GSSG ratio as an indicator of cellular health
Cosmetics & Personal Care (Rapidly Growing Segment)
The GSSG segment is gaining significant traction in cosmetics, where it is valued for its role in skin brightening and anti-aging treatments.
Key Cosmetic Applications:
Skin-brightening formulations — A clinical trial demonstrated that a 2% oxidized glutathione lotion decreased the melanin index (p<0.05), total epidermal water loss (TEWL) (p<0.05), and wrinkles (p<0.01)
Anti-aging skincare — combating oxidative stress and promoting skin health
Skin condition improvement — both topical and oral Glutathione are effective skin-lightening agents
Protective formulations — defending against environmental oxidative damage
Key Clinical Finding: Topical GSSG is safe and effectively whitens the skin and improves skin condition in healthy women.
Nutraceuticals & Dietary Supplements
Oxidized Glutathione is increasingly included in dietary supplements aimed at enhancing the body’s natural detoxification processes:
Detoxification support — aiding in the removal of harmful substances from the body
Antioxidant protection — helping to protect cells from oxidative stress
Immune support — supporting the body’s natural defense mechanisms
Anti-aging supplements — reducing oxidative stress to slow cellular aging
Functional Foods & Beverages
GSSG is applied in food, beverages, and health care products across a wide range of industries.
Product Name: Bulk Oxidized Glutathione (氧化型谷胱甘肽, L-Glutathione Oxidized, oxidized glutathione, oxiglutatione, glutathione disulfide, GSSG)
Appearance: A white to off-white powder
Cas Number: 27025-41-8
Molecular Formula: C20H32N6O12S2
Molecular Weight: 612.6 g/mol
Chemical Name: (2S)-2-amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
HS Code: 2930909099 (Other organic sulfur compounds-其他有机硫化合物)
Suitability to be shipped by air as common goods: Suitable, and it is safe to be shipped by air as common goods.
Grade: Pharma-Grade/Food-Grade
Purity or Assay: 99%
Standards: Current Enterprise Standards
Manufacturer Certificates available: GMP/ISO
Manufacturer Documents Available: COA/MSDS/MOA
Supply Capability: 200KG per month
MOQ: 100G
Price Ideas In 2025: 3000~4000USD/KG for food-grade (Contact us by WhatsApp for more detailed and updated prices)
Lead Time: 2~3 days for quantities less than 50KG, 1~2 days for orders less than 500G.
Stock Status: Over 50KG
Shipping Temperature: Room temperature
Storage: 2~8 °C
Technical Data:
Solubility: Freely soluble in water
Specific optical rotation: -96°~-106°
Heavy metals: NMT10ppm
Arsenic: NMT2ppm
Moisture/water: NMT6%
Residue on ignition: NMT0.5%
Purity: 98% as min
If you require bulk oxidized glutathione with CAS 27025-41-8 for manufacturing nutritional supplements or cosmetics, please contact us for a free quote.
OCTAGONCHEM is the leading glutathione manufacturer in China, offering competitive prices and prompt shipments after your order confirmation.
FAQs About Our Bulk Oxidized Glutathione
Q1: Is your Oxidized Glutathione suitable for pharmaceutical use?
Yes, our Oxidized Glutathione is manufactured under Good Manufacturing Practice (GMP) conditions. It complies with the United States Pharmacopeia (USP), European Pharmacopeia (EP), and Japanese Pharmacopeia (JP) standards, making it suitable for use in pharmaceutical formulations.
Q2: Can I use this API for compounding pharmacies or sterile preparations?
Absolutely. We provide documentation and packaging tailored for sterile and non-sterile compounding, including a certificate of analysis and stability data upon request.
Q3: Do you provide documentation required for regulatory approvals?
Yes, we offer comprehensive regulatory support, including Certificates of Analysis (CoA), Drug Master Files (DMF), Current Good Manufacturing Practice (CGMP) certificates, and pharmacopeial certificates specific to your region.
Q4: What is the minimum order quantity for API importers?
We work with both small- and large-scale clients. The MOQ is flexible and depends on your specific requirements. Please get in touch with us to discuss your particular needs.
Q5: Do you offer samples for quality evaluation?
Yes, we provide samples for authorized testing by your quality control team to ensure compliance before bulk orders.
Q6: Do international regulatory bodies inspect your facilities?
Yes, our manufacturing facilities are regularly audited and approved for compliance with international Good Manufacturing Practice (GMP), ISO, and FDA standards.
Q7: Can you support large-scale, global distribution and customs documentation?
Absolutely. We have experience delivering globally, with complete import/export documentation, including a certificate of origin, and can assist with local customs clearance.
Q8: Do you offer customized packaging or stability studies for Oxidized Glutathione?
Yes. Whether you need light-sensitive, moisture-proof drum packaging or batch-specific stability studies, we can accommodate your formulation requirements.
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