What Is Sobetirome (GC-1)?
Sobetirome, also known as GC-1 and QRX-431, is a white to off-white solid.
It is one of our most competitive small molecules, along with paxalisib and mirogabalin.
Sobetirome is a thyroid hormone receptor isoform beta-1 liver-selective analog with antilipidemic and antiatherosclerotic activity.
In animal models, it reduces serum lipids and decreases cholesterol levels.
In human models, it lowers plasma LDL cholesterol and reduces plasma triglycerides. Its liver-selective activity helps avoid the side effects of many other thyromimetic agents.
What Is Sobetirome Used For?
Sobetirome is a synthetic thyroid hormone that has been studied for its potential use in treating various medical conditions.
It is not currently approved for use in humans, as it is still in the early stages of development and clinical trials.
One potential use of sobetirome is for hypothyroidism, a condition in which the thyroid gland does not produce enough hormones.
Sobetirome increases thyroid hormone levels in animals and may also be effective in treating hypothyroidism in humans.
Another potential use of sobetirome is for obesity.
Sobetirome increases metabolism and reduces body weight, and it may be effective for weight loss.
In addition to these two potential uses, sobetirome may also improve cognitive function and memory and treat conditions such as diabetes and metabolic syndrome.
How Much Does Sobetirome Cost?
Although sobetirome has been studied as an active small molecule for a long time, it is still used primarily in lab research.
There is no GMP or FDA approval in China or the USA in 2021.
If you need it for research, the unit price for 1g is around 2500 USD.
If 1g is too much, you can contact us for smaller quantities, such as 50mg or 100mg.
We have a mature synthesis route for a stable supply; contact us anytime for a quote.
Disclaimer:
This content is for informational purposes only and is intended for business-to-business communication within the pharmaceutical industry. It is not intended as medical advice. The manufacture, import, and use of API must comply with all applicable laws and regulations in the relevant country or region.
This blog post is informational only and does not constitute medical advice.
Always consult a healthcare professional before starting any new medication or treatment.
