What Is Bupropion Hydrochloride?

bupropion hcl structure
Bupropion Hydrochloride API Chemical Structure

What Is Bupropion Hydrochloride Used For?

Bupropion hydrochloride API, also the active ingredient in Wellbutrin, is a medication that is commonly used to treat depression and seasonal affective disorder.

It is a white crystalline powder soluble in water and ethanol.

It is a weak blocker of the neuronal uptake of serotonin, dopamine, and norepinephrine and is a central nicotinic acetylcholine receptor antagonist.

Bupropion is a selective dopamine and norepinephrine reuptake inhibitor (SNRI), which means that it works by increasing the levels of these neurotransmitters in the brain. This can help to improve mood and alleviate the symptoms of depression.

bupropion hcl is used to quit smoking off-label

In addition to its use in the treatment of depression, bupropion hydrochloride is also sometimes used to help people quit smoking.

It is believed to work by reducing the cravings and withdrawal symptoms that are associated with quitting smoking.

Bupropion HCl is available in both immediate-release and extended-release forms and is typically taken orally once or twice daily.

One of the main advantages of bupropion hydrochloride is that it is less likely to cause sexual side effects than many other antidepressants.

This is because it does not affect the levels of serotonin in the brain, which is one of the main neurotransmitters that is involved in sexual function.

As a result, many people find that bupropion hydrochloride is a good option if they are experiencing sexual side effects from other antidepressants.

Is Bupropion Suitable For Weight loss?

bupropion HCl is used for weight loss

If you are wondering whether it can be used for weight loss or not, guess what, there is one pill marketed as CONTRAVE® on the market for weight loss.

The weight loss pill is compounded together with naltrexone.

Clinical studies were showing that CONTRAVE significantly realized weight loss when combined with a diet and exercise program.

It also achieved greater mean weight loss in women over the 8 weeks alone.

So the answer is yes, it is used for weight loss and showed certain effects.

Please note, don’t take it for weight loss without consulting your doctor. 

How Much Does Bupropion HCl API Cost?

For commercial order quantities of pure bupropion powder over 200 KG, certified with GMP and DMF, our price is around 130USD per kg.

If you only need 1kg as a trial order, our price is around 300usd.

Our price for 5~10kg is around 180~190 USD/KG.

Please check its export price from India so you will have a general idea.

From the screenshot above, we can see the average export price from India is 75usd per kg and the largest buyer for it is Canada, buying 13 Ton.

No idea how the prices to South Korea can be 137usd per kg, maybe too much commission added, who knows.

Anyway, if you need the latest cost updated, feel free to contact us anytime.


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