Tasimelteon vs Ramelteon

Patients having difficulty sleeping may receive prescriptions from doctors for different medications, such as melatonin, ramelteon, or tasimelteon.

It all depends on their symptoms.

But not everyone knows the difference between ramelteon and tasimelteon.

We have listed several points comparing the two ingredients, and we hope they are helpful to you.

1. Usage differences as medicines and approval date by the US FDA

People mainly use ramelteon for delayed sleep onset, one particular symptom of insomnia.

It is marketed as Rozerem and was approved by the US FDA in 2005. It is a good, non-addictive sleep medicine.

Tasimelteon, marketed as Hetlioz, treats sleep disorders, especially non-24-hour sleep-wake disorders. The US FDA first approved it in 2013.

It is approved to help blind people get their sleep cycle back on track.

2. Safety

Ramelteon is regarded as safe to use for people over 65 years old.

Tasimelteon has no guarantee of safety in this aspect. None of them is recommended for children, though.

3. Cost difference

The price of pure ramelteon is less than 1/10 of that of tasimelteon.

In 2023, the price of tasimelteon API will be around 11,000 USD per gram, while the cost of ramelteon will be about 10 USD per gram.

Synthesis difficulties can cause cost differences related to market demand quantity and manufacturing capacity.

When the demand quantity is commercial, the price will quickly descend from heaven to earth.

Meanwhile, tasimelteon is a relatively novel molecule compared with ramelteon; its annual consumption remains small.

4. Stability

The triangle cycle from Tasimelteon, which is very sensitive to light, heat, and moisture, can be seen in its structure.

All our molecules are packed in amber bottles or alu-foil bags.

We need to take extra care of it.

To sum up, tasimelteon and ramelteon are both used for insomnia, but for different types. Ramelteon is comparatively safer and much cheaper.

Tasimelteon is a relatively new molecule, and its safety will be assessed by future reported side effects.

If you have different opinions, comment below or contact us directly.