Breaking News: Favipiravir clears Corona Virus in 4 days
Favipiravir Cures Covice, What Is Favipiravir?
Favipiravir, an RNA polymerase (RdRp) inhibitor, is a broad-spectrum anti-flu virus ingredient.
It works by interfering with viral genetic replication to prevent viral reproduction.
Fujifilm Holdings developed it as the original manufacturer.
On March 24, 2014, the Ministry of Health, Labor, and Welfare approved Fujifilm Holdings’ Favipiravir tablets for the treatment of new and recurrent influenza under the trade name Avigan.
As the leading Favipiravir Manufacturer in China, we are very concerned about the clinical trials of favipiravir for coronavirus.
After the coronavirus outbreak in 2019, researchers have explored many antiviral drugs as potential cures in both new and old, such as remdesivir, chloroquine phosphate, Favipiravir, lopinavir/ritonavir, Chinese traditional medicine, acupuncture, and even Tai Chi.
Favipiravir, the second most popular remedy against coronavirus after Remdisvir from Gilead, has attracted many research institutions to launch clinical trials for COVID-19 pneumonia.
Favipiravir Clinical Trial Results
On Feb 14th, 2020, Preliminary clinical results of Favipiravir in China came out for the treatment of coronavirus pneumonia.
It eliminated viruses within 4 days with good safety and tolerance.
Viral clearance has been the gold standard for evaluating the clinical efficacy of antiviral drugs.
The clinical study conducted in Shenzhen showed that favipiravir relieved the progression of coronavirus by accelerating virus clearance.
In this clinical trial, researchers treated 35 patients with COVID-19 pneumonia with Favipiravir (3200 mg on the first day, 1200 mg/day on the 2nd to 14th day, and 600 mg twice daily); the virus was eliminated within 14 days.
There was another group of 45 patients with COVID-19 pneumonia treated with lopinavir/ritonavir tablets (400mg/100mg, twice daily orally), matched for age, gender, and disease severity.
Researchers compared the two groups on median time from drug administration to virus clearance, chest imaging improvement rate, and safety.
The comparison showed positive results in the favipiravir group: the median time was shorter for virus clearance, with a median (interquartile range) of 4 days (2.5-9 days) and 11 days (8-13 days) in the lopinavir/ritonavir group, with significant differences between these two groups ( P <0.001).
After controlling for potential confounding factors (age, time to onset, fever) and other potential factors, Favipiravir remains an independent factor associated with improved chest imaging and early virus clearance.
Compared with the lopinavir/ritonavir group, the favipiravir group had fewer adverse reactions and better toleration.
The research results have been submitted to the journal of the Chinese Academy of Engineering.
Fastest Drug Approval From China FDA
In 2016, Hisun Pharma from China signed an exclusive patent authorization agreement with Fuji Chemical and has been researching Favipiravir ever since.
On February 15th, 2020, Hisun Pharma announced that their Favipiravir tablets were formally approved by the State Food and Drug Administration to be marketed for the treatment of new or recurrent influenza in adults (only when other antiviral drugs are ineffective). Following the outbreak of the coronavirus, Hisun Pharma submitted a marketing application to the State Food and Drug Administration urgently.
The entire approval process, including drug acceptance from CDE (China Drug Evaluation), production approval, and marketing approval, took only 15 days, the fastest in China drug approval history.
One representative from Hisun said: ‘Once Favipiravir is approved for marketing, it can be used by clinical experts on a small scale to treat coronavirus pneumonia’.
If more clinical evidence shows that favipiravir is effective in the treatment of COVID-19 pneumonia, it will serve as another option to help the patients.’
How Much Does Favipiravir API Cost?
If you are looking for Favipiravir for research, please check our pricing ideas below:
For 10 grams, our price is about 150 USD/g.
For costs of other quantities, please contact us directly.
Other Possible Treatments For Covid-19
- Remdesivir
- Ritonavir with lopinavir
- Ribavirin
- Galidesivir（BCX4430)
- Disulfiram
- Chloroquine Phosphate
- Hydroxychloroquine Sulfate
- Nitazoxanide
- Umifenovir
- Oseltamivir Phosphate
- Danoprevir
- Brilacidin
- Darunavir with cobicistat
- Arbidol Hydrochloride with Umifenovir
Disclaimer:
This content is for informational purposes only and is intended for business-to-business communication within the pharmaceutical industry. It is not intended as medical advice. The manufacture, import, and use of API must comply with all applicable laws and regulations in the relevant country or region.
This blog post is informational only and does not constitute medical advice.
Always consult a healthcare professional before starting any new medication or treatment.
