FDA Approved Bacitracin Zinc For Sale!

Pure Active Pharmaceutical Ingredients bacitracin zinc structure

Bacitracin Zinc 1405-89-6 Structure

Product Name: Bacitracin Zinc

Cas No.: 1405-89-6

Chemical Formula: C66H101N17O16SZn

Molecular Weight: 1486.067

We have USFDA Approval for zinc bacitracin. It is suitable for producing pharmaceutical formulations. Our quality meets USP41 requirements. Free Bacitracin zinc sample available for quality testing. Our packing is 20kg/Carton. MOQ starts at 1KG.

Looking for FDA-Approved Bacitracin Zinc Manufacturer? Contact Us Now!

What is Bacitracin zinc?

Bacitracin Zinc is a complex of zinc and bacitracin. It is a white or off-white powder with its characteristic odor and bitter taste. It is one of our USFDA-Approved pharmaceutical ingredients along with Bacitracin. It is an effective narrow-spectrum antibiotic peptide with a similar antibacterial spectrum to penicillin, mainly for Gram-positive cocci and bacilli. Zinc bacitracin powder also exerts a certain inhibitory effect on several Gram-negative bacteria, spirochetes, and actinomycetes with attributes of high efficiency, low toxicity, and low residue.

Technically speaking, bacitracin zinc powder is bacitracin with zinc (bacitracin zinc salt) solid, a mixture of related cyclic peptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. These peptides disrupt Gram-positive bacteria by interfering with the cell wall and peptidoglycan synthesis. Metal zinc within bacitracin zinc makes bacitracin zinc powder more stable than bacitracin powder.

First thing first, we must mention it upfront: there are two types of bacitracin zinc powder: the first type is high-potency type Pharm-Grade (Potency No Less Than 65IU/MG). The second type is Feed-Grade or Industrial-Grade (Potency Less than 40IU/MG). Here we mainly discuss pharm-grade zinc bacitracin.

How is Bacitracin Zinc Produced?

1. Fermentation process using Bacillus subtilis and B. licheniformis to get bacitracin solution. (Bacitracin solution is an extraction and separation solution of a Bacillus subtilis and a B-type Bacillus licheniformis fermentation broth with a potency of no less than 5000 u/ml and a conductance of less than 2000 μs/cm).

2. An alkaline solution is added to the bacitracin solution to adjust the pH as 8 to 11, add inorganic zinc salt, adjust pH as 5 to 7 with an inorganic acid, stir for 1 to 2 hours, and let stand for 5 to 10 hours. (The alkaline solution can be either ammonia water or sodium hydroxide. The inorganic zinc salt is one of zinc oxide, zinc chloride, and zinc sulfate. The inorganic acid is one of hydrochloric acid and sulfuric acid.)

3. Bacitracin zinc is then obtained by separation, drying, pulverization, sieving, inspection.

The total content of bacitracin A should be greater than 40.0%, the total amount of bacitracin A, B” B2 and B3 should be greater than 70.0%, Potency should be no less than 65IU/MG.

Zinc Bacitracin obtained by this method could be used for medicinal preparations such as injections and ointments.

What can bacitracin zinc be used for?

Bacitracin zinc can be used by combining with other topical antibiotics (usually Polymyxin B sulfate and Neomycin) as an ointment (well-known as Pfizer’s Neosporin). It is used for the topical treatment of a variety of localized skin infections, as well as for the prevention of wound infections.

It is also indicated for Empyema, Infection NOS, Pneumonia, Corticosteroid-responsive Dermatosis, Infection in minor cuts, scrapes, or burns, Inflammatory ocular disease, etc (Made into cortisporin ophthalmic ointment).

There is zinc bacitracin ointment used as first aid to help prevent infection in minor cuts, scrapes, burns.

There are people using formulations of bacitracin zinc for acne when acne pimples are infected. People would combine bacitracin zinc ointment with cleansers containing benzoyl peroxide to kill bacteria that might colonize an injured pimple.

However, zinc bacitracin doesn’t always cure acne. Some people report no improvement or even worse outbreaks after applying it.

There are bacitracin zinc ophthalmic solutions of non-ointment forms for eye infections. There are also Ophthalmic Ointments of Bacitracin Zinc and Polymyxin B Sulfate indicated for the treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria.

What are bacitracin zinc dosages?

bacitracin zinc ointment

Bacitracin zinc Topical Ointment, Strength: 500IU/G [Each gram contains Bacitracin Zinc (equal to 500 bacitracin units)]

Bacitracin zinc Ophthalmic Ointment of 3.5 grams in tubes. Each gram contains bacitracin zinc equivalent to 500 bacitracin units, polymyxin B sulfate equivalent to 10,000 polymyxin B units, mineral oil, and white petrolatum.

10 Person First Aid Kit including: Bacitracin zinc (400 [iU]/1g) + Acetaminophen (325 mg/1) + Acetylsalicylic acid (325 mg/1) + Benzalkonium chloride (0.13 g/100g) + Benzalkonium chloride (0.40 mL/100mL) + Benzocaine (6 mL/100mL) + Ethanol (60 mL/100mL) + Ibuprofen (200 mg/1) + Lidocaine (0.5 1/100g) + Neomycin sulfate (5 mg/1g) + Polymyxin B sulfate (5000 [iu]/1g) + Water (98.6 mL/100mL)

Bacitracin Zinc Soluble Powder (Bacitracin Zinc Soluble Powder is a mixture of Bacitracin Zinc and zinc proteinates. It contains not less than 90.0 percent and not more than 120.0 percent of the labeled amount of having a bacitracin concentration that is nominally bacitracin.)

bacitracin zinc ointment for eczema

Bacitracin Zinc and Polymyxin B Sulfate Ointment

Polymyxin B Sulfate and Bacitracin Zinc Topical Aerosol

Polymyxin B Sulfate and Bacitracin Zinc Topical Powder

Bacitracin zinc vs zinc oxide?

zinc oxide is also used in many products for skin as zinc bacitracin, but what is the main difference between zinc oxide and bacitracin zinc?

Excluding their chemical property differences, Zinc Oxide is an inorganic chemical, Bacitracinc zinc is an organic peptide, they have different cas no, molecular weight etc, zinc oxide is mainly used to treat skin conditions, including dermatitis, itching due to eczema, diaper rash and acne. Bacitracin zinc is mainly used as an antibiotic for infections of wounds. Below is detailed zinc oxide usage introductions and comparison.

Zinc oxide is contained in baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. It is also a component in tape (zinc oxide tape) used by athletes as a bandage to prevent soft tissue damage during workouts.

Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light. Zinc oxide blocks both UVA (320–400 nm) and UVB (280–320 nm) rays of ultraviolet light to prevent sunburn. It works as the broadest spectrum UVA and UVB absorber. Zinc oxide and the other most common physical sunscreen, titanium dioxide, are considered to be nonirritating, nonallergenic, and non-comedogenic. Whereas bacitracin zinc works by killing bacteria in the wounds to get a quick healing.

But the Zinc oxide cost is only 1/50 of bacitracin zinc price, if not even less.

Bacitracin zinc side effects & contraindications

Side Effects of bacitracin zinc includes but not limited to: skin burning, red skin, skin irritation, skin dryness, itching, stinging, scaling and sores.

Bacitracin Zinc is contraindicated in individuals who have shown hypersensitivity to any of its components (Bacitracin zinc is a mixture anyway).

What is the Bacitracin Zinc Price? (Last update 2019.12.11)

Zinc bacitracin cost of commercial order quantities is about 600usd/kg(60IU/MG).

Feed-grade bacitracin zinc powder price is about 300usd/kg. (40IU/MG)

15% bacitracin zinc premix price is about 3usd/kg, 2usd/kg for 10% type for commercial order quantities.

For more accurate prices, please contact us directly.

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